Description

3-Bromo-2-fluoro-5-methylpyridine (CAS No. 17282-01-8) is a high-purity halogenated pyridine derivative designed for advanced research and industrial applications. This compound, with the molecular formula C₆H₅BrFN, is a versatile building block in pharmaceutical, agrochemical, and material science research. Its unique structure, featuring bromo and fluoro substituents on the pyridine ring, enables selective functionalization and cross-coupling reactions, making it invaluable for synthetic chemistry. Available in various quantities, our product is rigorously tested to ensure ≥98% purity (HPLC/GC) and is supplied with comprehensive analytical data (NMR, MS). Suitable for use in Suzuki-Miyaura, Buchwald-Hartwig, and other metal-catalyzed reactions, this compound is packaged under inert conditions to guarantee stability and longevity.

Properties

• CAS Number: 17282-01-8
• Complexity: 99.1
• IUPAC Name: 3-bromo-2-fluoro-5-methyl-pyridine
• InChI: InChI=1S/C6H5BrFN/c1-4-2-5(7)6(8)9-3-4/h2-3H,1H3
• InChI Key: FWKQBHMQYXTOTD-UHFFFAOYSA-N
• Exact Mass: 188.95894
• Molecular Formula: C6H5BrFN
• Molecular Weight: 190.01
• SMILES: CC1=CC(=C(N=C1)F)Br
• Topological: 12.9
• Monoisotopic Mass: 188.95894
• Synonyms: 3-Bromo-2-fluoro-5-methylpyridine, 17282-01-8, DTXSID70618373, DTXCID00569127, 807-945-5, 3-bromo-2-fluoro-5-picoline, MFCD03095305, 2-FLUORO-3-BROMO-5-METHYLPYRIDINE, 2-fluoro-3-bromo-5-picoline, SCHEMBL115732, 5-Bromo-6-fluoro-3-picoline, FWKQBHMQYXTOTD-UHFFFAOYSA-N, BCP22131, CS-D0947, BBL100995, SBB091032, STL554789, AKOS005063652, AB13665, DS-0586, AC-23352, SY020983, DB-028380, 3-BROMO-2-FLUORO-5-METHYL-PYRIDINE, B4122, EN300-127558, 3-Bromo-2-fluoro-5-picoline (3-Bromo-2-fluoro-5-methylpyridine)

Application

3-Bromo-2-fluoro-5-methylpyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. Its reactive halogen sites facilitate the construction of complex heterocycles for drug discovery, particularly in kinase inhibitors and CNS-targeted therapies. In agrochemical research, it is employed to develop novel pesticides and herbicides with enhanced efficacy. The compound’s stability under diverse reaction conditions also makes it ideal for material science applications, such as ligand design for catalysis.

Safety and Hazards

GHS Hazard Statements

• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (50%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (50%)
• Skin Irrit. 2 (100%)
• Eye Dam. 1 (50%)
• Eye Irrit. 2 (50%)
• STOT SE 3 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.