Description

3-Aminopyridine (CAS No. 462-08-8) is a high-purity organic compound with the molecular formula C₅H₆N₂, widely utilized in pharmaceutical, agrochemical, and materials research. This heterocyclic amine, also known as pyridin-3-amine, features an amino group at the 3-position of the pyridine ring, offering versatile reactivity for nucleophilic substitution, coordination chemistry, and as a building block for complex molecular architectures. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC), with controlled moisture and residual solvent levels, making it ideal for sensitive applications. Available in scalable quantities from milligrams to kilograms, it is supplied in amber glass vials or tamper-evident HDPE bottles to ensure stability. Suitable for use as a precursor in drug discovery, ligand synthesis, and functionalized polymer development.

Properties

• CAS Number: 462-08-8
• Complexity: 54
• IUPAC Name: pyridin-3-amine
• InChI: InChI=1S/C5H6N2/c6-5-2-1-3-7-4-5/h1-4H,6H2
• InChI Key: CUYKNJBYIJFRCU-UHFFFAOYSA-N
• Exact Mass: 94.053098200
• Molecular Formula: C5H6N2
• Molecular Weight: 94.11
• SMILES: C1=CC(=CN=C1)N
• Topological: 38.9
• Monoisotopic Mass: 94.053098200
• Physical Description: Other Solid
• Boiling Point: 483.8 °F
• Melting Point: 147.2 °F
• Flash Point: 190.4 °F
• Vapor Pressure: 0.43 [mmHg]
• Synonyms: 3-AMINOPYRIDINE, 462-08-8, pyridin-3-amine, 3-Pyridinamine, 3-Pyridylamine, m-Aminopyridine, Amino-3 pyridine, pyridin-3-ylamine, Pyridine, 3-amino-, 3-amino pyridine, beta-Aminopyridine, .beta.-Aminopyridine, 3-Pyridinylamine, MFCD00006400, pyridin-3-yl-amine, CHEMBL25541, DTXSID9047461, 69JE8P2L84, NSC-15040, DTXCID7027461, CAS-462-08-8, EINECS 207-322-2, NSC 15040, BRN 0105692, UNII-69JE8P2L84, 3-aminopryidine, 3-aminopyridin, AI3-52546, 3-amino-pyridin, 3-Amino pyridin, 3-pyridine amine, pyridine-3-amine, 3-Amino-pyridine, pyridine-3-ylamine, pyridin-3-yl amine, 5-AMINOPYRIDINE, 3-Aminopyridine, 99%, 3AP, WLN: T6NJ CZ, SCHEMBL19628, 5-22-09-00003 (Beilstein Handbook Reference), SCHEMBL131010, SCHEMBL334083, SCHEMBL335021, SCHEMBL1397535, SCHEMBL2067345, SCHEMBL9111303, .BETA.-AMINOPYRIDINE [MI], 3-Pyridinamine; beta-Aminopyridine, BCP22961, NSC15040, Tox21_201650, Tox21_303451, BDBM50122005, CX1211, SBB004395, STL163954, AKOS000119614, FA02057, PS-9358, UN 2671, UN-2671, m-Aminopyridine [UN2671] [Poison], NCGC00249092-01, NCGC00257364-01, NCGC00259199-01, BP-12818, DB-028364, A0413, NS00020819, ST45255301, EN300-21243, A827009, AC-907/25014070, Q4634118, F1995-0204, Z104494800, InChI=1/C5H6N2/c6-5-2-1-3-7-4-5/h1-4H,6H

Application

3-Aminopyridine serves as a key intermediate in the synthesis of pharmaceuticals, including neuromodulators and kinase inhibitors. It is employed in agrochemical research for developing crop protection agents due to its bioactivity. The compound also acts as a ligand in catalytic systems and a monomer for conductive polymers in material science.

Safety and Hazards

GHS Hazard Statements

• H300 (15%): Fatal if swallowed [Danger Acute toxicity, oral]
• H301 (85%): Toxic if swallowed [Danger Acute toxicity, oral]
• H311 (81.7%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315 (88.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (88.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H331 (73.3%): Toxic if inhaled [Danger Acute toxicity, inhalation]
• H335 (80%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H373 (70%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
• H400 (16.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410 (16.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 2 (15%)
• Acute Tox. 3 (85%)
• Acute Tox. 3 (81.7%)
• Skin Irrit. 2 (88.3%)
• Eye Irrit. 2 (88.3%)
• Acute Tox. 3 (73.3%)
• STOT SE 3 (80%)
• STOT RE 2 (70%)
• Aquatic Acute 1 (16.7%)
• Aquatic Chronic 1 (16.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.