Description

3-Amino-9-ethylcarbazole (CAS 132-32-1) is a high-purity organic compound with the molecular formula C₁₄H₁₄N₂, widely utilized in biochemical and industrial research. This carbazole derivative, also known by its IUPAC name 9-ethylcarbazol-3-amine, features an ethyl group at the 9-position and an amino group at the 3-position of the carbazole ring, enhancing its reactivity and solubility in organic solvents. With a molecular weight of 210.28 g/mol, it is supplied as a crystalline solid with >98% purity, verified by HPLC and NMR. Ideal for use as a chromogenic substrate in peroxidase-mediated reactions, it produces an insoluble red-brown precipitate upon oxidation, making it invaluable in immunohistochemistry (IHC) and blotting techniques. Store at 2-8°C in a tightly sealed container to maintain stability.

Properties

• CAS Number: 132-32-1
• Complexity: 253
• IUPAC Name: 9-ethylcarbazol-3-amine
• InChI: InChI=1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3
• InChI Key: OXEUETBFKVCRNP-UHFFFAOYSA-N
• Exact Mass: 210.115698455
• Molecular Formula: C14H14N2
• Molecular Weight: 210.27
• SMILES: CCN1C2=C(C=C(C=C2)N)C3=CC=CC=C31
• Topological: 31
• Monoisotopic Mass: 210.115698455
• Physical Description: 3-amino-9-ethylcarbazole is a tan powder.
• Color/Form: Crystalline compound
• Melting Point: 208 to 212 °F
• Solubility: less than 1 mg/mL at 68 °F
• Synonyms: 3-AMINO-9-ETHYLCARBAZOLE, 132-32-1, 9-Ethyl-9H-carbazol-3-amine, 3-Amino-N-ethylcarbazole, 9H-Carbazol-3-amine, 9-ethyl-, Carbazole, 3-amino-9-ethyl-, 9-Ethylcarbazol-3-ylamine, 9-ethyl-9H-carbazol-3-ylamine, HSDB 4108, EINECS 205-057-7, 8Q2BG27JBU, NSC 67709, BRN 0174969, DTXSID1030319, AI3-50580, 9-ethyl-3-carbazolamine, NSC-67709, DTXCID5055, 4-22-00-04936 (Beilstein Handbook Reference), 3-AMINO-9-ETHYLCARBAZOLE [HSDB], 3AminoNethylcarbazole, 9Ethyl9Hcarbazol3amine, 3-amino-n-ethylcarbazol, Carbazole, 3amino9ethyl, 9HCarbazol3amine, 9ethyl, 9-Ethylcarbazol-3-amine, MFCD00004964, 9-ethylcarbazole-3-ylamine, AEC, 50X, EN300-20033, WLN: T B656 HNJ DZ H2, 3-amino-9-ethylcarbazole, tech., 90%, CAS-132-32-1, SMR000017024, 3-amino-9-ethylcabazole, UNII-8Q2BG27JBU, 9-ethyl-3-carbazolylamine, NCIOpen2_003471, Oprea1_198966, Oprea1_584611, SCHEMBL37700, MLS000080736, MLS000102910, BIDD:GT0028, SCHEMBL869763, CHEMBL327035, IFLab1_003889, OXEUETBFKVCRNP-UHFFFAOYSA-, 3-Amino-9-ethylcarbazole, tablet, 9-Ethyl-9H-carbazol-3-amine #, CHEBI:122149, BDBM626079, HMS1423A17, HMS2182N09, NSC67709, NSC96640, Tox21_202398, Tox21_303548, 3-Amino-9-ethylcarbazole, Technical, BBL009278, NSC-96640, SBB000498, STK835258, AKOS000119667, BS-4192, CCG-202922, CS-W015102, EA00384, HY-W014386, NCGC00064254-03, NCGC00257477-01, NCGC00259947-01, ST031682, SY057088, 3-Amino-9-ethylcarbazole, >=95%, powder, A1508, A2167, EU-0066617, NS00024205, F16805, AE-508/36396054, SR-01000597194, SR-01000597194-1, Q21099619, F0848-0399, 3-Amino-9-ethylcarbazole, for HPLC derivatization, >=97.0% (HPLC), InChI=1/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3

Application

3-Amino-9-ethylcarbazole is primarily used as a chromogen in immunohistochemistry (IHC) and Western blotting, where it forms a vivid red-brown precipitate upon reaction with horseradish peroxidase (HRP). It is also employed in the synthesis of dyes, pharmaceuticals, and organic semiconductors due to its electron-rich carbazole core. Researchers leverage its properties in photodynamic therapy and as a building block for fluorescent probes.

Safety and Hazards

GHS Hazard Statements

• H301: Toxic if swallowed [Danger Acute toxicity, oral]
• H350: May cause cancer [Danger Carcinogenicity]

Precautionary Statements

• P203, P264, P270, P280, P301+P316, P318, P321, P330, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (81.5%)
• Carc. 1B (94.4%)

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