Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair (2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol C11H11ClIN3O3 CAS 178995-71-6

(2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS No. 178995-71-6) is a high-purity nucleoside analog designed for advanced biochemical and pharmaceutical research. With the molecular formula C11H11ClIN3O3, this compound features a chlorinated and iodinated pyrrolo[2,3-d]pyrimidine core, coupled with a hydroxymethyl-substituted tetrahydrofuran ring, offering unique reactivity for nucleoside-based studies. Its stereospecific configuration ( 2R,3S,5R ) ensures precise interactions in enzymatic and receptor-binding assays. Ideal for medicinal chemistry, antiviral research, and nucleotide analog development, this compound is supplied with comprehensive analytical data (HPLC, NMR, MS) to guarantee quality and reproducibility. Store under inert conditions at -20°C to maintain stability.

Category:

Description

(2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS No. 178995-71-6) is a high-purity nucleoside analog designed for advanced biochemical and pharmaceutical research. With the molecular formula C11H11ClIN3O3, this compound features a chlorinated and iodinated pyrrolo[2,3-d]pyrimidine core, coupled with a hydroxymethyl-substituted tetrahydrofuran ring, offering unique reactivity for nucleoside-based studies. Its stereospecific configuration (2R,3S,5R) ensures precise interactions in enzymatic and receptor-binding assays. Ideal for medicinal chemistry, antiviral research, and nucleotide analog development, this compound is supplied with comprehensive analytical data (HPLC, NMR, MS) to guarantee quality and reproducibility. Store under inert conditions at -20°C to maintain stability.

Properties

  • CAS Number: 178995-71-6
  • Complexity: 340
  • IUPAC Name: (2R,3S,5R)-5-(4-chloro-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • InChI: InChI=1S/C11H11ClIN3O3/c12-10-9-5(13)2-16(11(9)15-4-14-10)8-1-6(18)7(3-17)19-8/h2,4,6-8,17-18H,1,3H2/t6-,7+,8+/m0/s1
  • InChI Key: IBTCDOMWNGACAS-XLPZGREQSA-N
  • Exact Mass: 394.95337
  • Molecular Formula: C11H11ClIN3O3
  • Molecular Weight: 395.58
  • SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C3=C2N=CN=C3Cl)I)CO)O
  • Topological: 80.4
  • Monoisotopic Mass: 394.95337
  • Synonyms: 178995-71-6, (2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, (2R,3S,5R)-5-(4-chloro-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)oxolan-3-ol, 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-iodo-, AKOS025402573, DB-120483

Application

This compound serves as a key intermediate in the synthesis of modified nucleosides for antiviral and anticancer drug discovery. Its halogenated pyrrolopyrimidine structure enables selective cross-coupling reactions in medicinal chemistry. Researchers utilize it to study enzyme inhibition mechanisms, particularly in viral polymerase targeting. It is also valuable for probing nucleotide metabolism and DNA/RNA interaction studies.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products