Atomfair 2,6-Difluoro-3-iodopyridine C5H2F2IN CAS 685517-67-3

2,6-Difluoro-3-iodopyridine (CAS: 685517-67-3) is a high-purity fluorinated pyridine derivative widely used in pharmaceutical and agrochemical research. With the molecular formula C5H2F2IN , this compound serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Negishi couplings. Its unique halogenated structure enables precise functionalization, making it invaluable for developing novel bioactive molecules, ligands, and materials. Packaged under inert conditions to ensure stability, our product undergoes rigorous QC testing (HPLC, NMR) to guarantee ≥98% purity, meeting the stringent demands of industrial and academic researchers.

Description

2,6-Difluoro-3-iodopyridine (CAS: 685517-67-3) is a high-purity fluorinated pyridine derivative widely used in pharmaceutical and agrochemical research. With the molecular formula C5H2F2IN, this compound serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Negishi couplings. Its unique halogenated structure enables precise functionalization, making it invaluable for developing novel bioactive molecules, ligands, and materials. Packaged under inert conditions to ensure stability, our product undergoes rigorous QC testing (HPLC, NMR) to guarantee ≥98% purity, meeting the stringent demands of industrial and academic researchers.

Properties

  • CAS Number: 685517-67-3
  • Complexity: 101
  • IUPAC Name: 2,6-difluoro-3-iodo-pyridine
  • InChI: InChI=1S/C5H2F2IN/c6-4-2-1-3(8)5(7)9-4/h1-2H
  • InChI Key: UTWLONSABCGCBR-UHFFFAOYSA-N
  • Exact Mass: 240.92000
  • Molecular Formula: C5H2F2IN
  • Molecular Weight: 240.98
  • SMILES: C1=CC(=NC(=C1I)F)F
  • Topological: 12.9
  • Monoisotopic Mass: 240.92000
  • Synonyms: 2,6-Difluoro-3-iodopyridine, 685517-67-3, DTXSID00599727, DTXCID10550485, 835-261-7, 3-Iodo-2,6-difluoropyridine, MFCD09743595, Pyridine,2,6-difluoro-3-iodo-, Pyridine, 2,6-difluoro-3-iodo-, 2,6-difluoro-3-iodo-pyridine, SCHEMBL1300595, SCHEMBL22716691, UTWLONSABCGCBR-UHFFFAOYSA-N, SBB099356, AKOS016038691, PS-7580, SY028905, DB-082130, CS-0036467, D5141, EN300-200840, W10872

2,6-Difluoro-3-iodopyridine is primarily employed as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its reactivity in palladium-catalyzed cross-coupling reactions facilitates the construction of complex heterocyclic scaffolds. Researchers also utilize it to develop PET radiotracers and liquid crystal materials due to its electron-withdrawing properties. Suitable for lab-scale and pilot-scale applications under controlled conditions.

Safety and Hazards

GHS Hazard Statements

  • H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (66.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (66.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (66.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (66.7%)
  • Acute Tox. 4 (66.7%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • Acute Tox. 4 (66.7%)
  • STOT SE 3 (66.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

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