Description

2,6-Dibromo-4-trifluoromethoxyaniline (CAS No. 88149-49-9) is a high-purity halogenated aniline derivative with the molecular formula C₇H₄Br₂F₃NO. This compound is characterized by its unique trifluoromethoxy and dibromo substitutions on the aromatic ring, making it a valuable intermediate in organic synthesis and pharmaceutical research. Its IUPAC name is 2,6-dibromo-4-(trifluoromethoxy)aniline, and it is supplied as a crystalline solid with ≥95% purity (HPLC). Ideal for researchers in medicinal chemistry, this compound is rigorously tested for consistency and stability, ensuring reliable performance in coupling reactions, electrophilic substitutions, and agrochemical applications. Packaged under inert gas to prevent degradation and stored in amber vials to protect from light.

Properties

• CAS Number: 88149-49-9
• Complexity: 190
• IUPAC Name: 2,6-dibromo-4-(trifluoromethoxy)aniline
• InChI: InChI=1S/C7H4Br2F3NO/c8-4-1-3(14-7(10,11)12)2-5(9)6(4)13/h1-2H,13H2
• InChI Key: JBSWOEGXMADXOU-UHFFFAOYSA-N
• Exact Mass: 334.85912
• Molecular Formula: C7H4Br2F3NO
• Molecular Weight: 334.92
• SMILES: C1=C(C=C(C(=C1Br)N)Br)OC(F)(F)F
• Topological: 35.3
• Monoisotopic Mass: 332.86117
• Synonyms: 88149-49-9, 2,6-dibromo-4-(trifluoromethoxy)benzenamine, 2,6-Dibromo-4-Trifluoromethoxyaniline, Benzenamine, 2,6-dibromo-4-(trifluoromethoxy)-, Dibromotrifluoro methoxyaniline, EQF477YZ64, 618-118-1, 2,6-Dibromo-4-(trifluoromethoxy)aniline, MFCD00153113, 2,6-dibromo-4-trifluoromethoxy aniline, 3,5-dibromo-4-aminotrifluoromethoxybenzene, C7H4Br2F3NO, 2-Amino-1,3-dibromo-5-(trifluoromethoxy)benzene, 2,6Dibromo-4-(trifluoromethoxy)aniline, 2,6-Dibromo-4-Trifluoro-Methoxy aniline, 3,5-Dibromo-4-amino(trifluoromethoxy)benzene, UNII-EQF477YZ64, SCHEMBL968221, DTXSID10371612, AKOS015854757, CS-W009845, PS-7016, 2,6-dibromo-4-trifluoromethoxy-aniline, 3.5-dibromo-4-aminotrifluoromethoxybenzen, AC-13858, SY016225, 2,6-dibromo-4-(trifluoro-methoxy)ani-line, 3,5-dibromo-4-aminotrifluoromethoxy benzene, DB-024274, 2,6-dibromo-4-(trifluoromethoxy)phenylamine, D3038, ST50320213

Application

2,6-Dibromo-4-trifluoromethoxyaniline serves as a key building block in the synthesis of advanced pharmaceutical intermediates, particularly for bioactive molecules with trifluoromethoxy motifs. It is utilized in cross-coupling reactions (e.g., Buchwald-Hartwig amination) to construct complex heterocycles. Researchers also employ it in agrochemical development for designing novel pesticides and herbicides due to its halogen-rich structure. Its electron-withdrawing properties make it suitable for materials science applications, such as liquid crystal and polymer modifiers.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.6%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.