Description

2,5-Difluorophenol (CAS No. 2713-31-7) is a high-purity fluorinated phenolic compound with the molecular formula C₆H₄F₂O. This aromatic organic compound features two fluorine atoms at the 2- and 5-positions of the phenol ring, offering unique reactivity and electronic properties for advanced synthetic applications. Ideal for pharmaceutical intermediates, agrochemical research, and material science, our 2,5-Difluorophenol is rigorously tested to meet the highest standards of purity and consistency. Available in various quantities with detailed analytical certificates (including GC/MS, NMR, and HPLC data), this product is essential for researchers requiring precise fluorinated building blocks. Store in a cool, dry place under inert atmosphere to maintain stability.

Properties

• CAS Number: 2713-31-7
• Complexity: 97.1
• IUPAC Name: 2,5-difluorophenol
• InChI: InChI=1S/C6H4F2O/c7-4-1-2-5(8)6(9)3-4/h1-3,9H
• InChI Key: INXKVYFOWNAVMU-UHFFFAOYSA-N
• Exact Mass: 130.02302107
• Molecular Formula: C6H4F2O
• Molecular Weight: 130.09
• SMILES: C1=CC(=C(C=C1F)O)F
• Topological: 20.2
• Monoisotopic Mass: 130.02302107
• Synonyms: 2,5-Difluorophenol, 2713-31-7, Phenol, 2,5-difluoro-, Phenol,2,5-difluoro-, INXKVYFOWNAVMU-UHFFFAOYSA-, DTXSID90181594, NSC 10288, DTXCID30104085, 608-045-3, inchi=1/c6h4f2o/c7-4-1-2-5(8)6(9)3-4/h1-3,9h, inxkvyfownavmu-uhfffaoysa-n, MFCD00042501, 53EYY8S7LA, NSC-10288, 1,4-Difluoro-2-hydroxybenzene, 2,5-difluoro-phenol, NSC10288, 2,5-difluoro phenol, phenol derivative, 5, 2,5-Bis(fluoranyl)phenol, UNII-53EYY8S7LA, SCHEMBL70273, 2,5-Difluorophenol, 95%, SCHEMBL752296, CHEMBL261219, SCHEMBL1039208, SCHEMBL29113025, BDBM26191, CS-D1368, SBB085755, AKOS005257731, AC-3785, CCG-325853, PS-9150, BP-20573, PD180173, SY007690, DB-023862, A5294, D2036, NS00122283, ST51038134, EN300-69698, Z401432098

Application

2,5-Difluorophenol serves as a versatile intermediate in the synthesis of fluorinated pharmaceuticals, including kinase inhibitors and antibacterial agents. Its electron-withdrawing fluorine atoms enhance reactivity in nucleophilic aromatic substitution (SNAr) reactions, making it valuable for constructing complex heterocycles. In material science, it is employed as a monomer for specialty polymers with enhanced thermal and chemical resistance. Additionally, it finds use in agrochemical research for developing novel pesticides and herbicides.

Safety and Hazards

GHS Hazard Statements

• H228 (100%): Flammable solid [Danger Flammable solids]
• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (91.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (91.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (91.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (89.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P240, P241, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501

Hazard Classes and Categories

• Flam. Sol. 1 (100%)
• Acute Tox. 4 (100%)
• Acute Tox. 4 (100%)
• Skin Irrit. 2 (91.7%)
• Eye Irrit. 2 (91.7%)
• Acute Tox. 4 (91.7%)
• STOT SE 3 (89.6%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.