Description

2,4-Difluoropyridine (CAS No. 34941-90-7) is a high-purity fluorinated pyridine derivative with the molecular formula C₅H₃F₂N. This heterocyclic compound is widely utilized in pharmaceutical research, agrochemical synthesis, and advanced material science due to its unique reactivity and structural properties. With a purity grade of ≥98%, our product is rigorously tested via GC-MS, NMR, and HPLC to ensure consistency and reliability for demanding applications. The compound is supplied in sealed, light-resistant containers under inert gas to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling protocols, and as a building block for fluorinated bioactive molecules. Available in quantities ranging from 1g to 1kg with custom packaging options.

Properties

• CAS Number: 34941-90-7
• Complexity: 76.8
• IUPAC Name: 2,4-difluoropyridine
• InChI: InChI=1S/C5H3F2N/c6-4-1-2-8-5(7)3-4/h1-3H
• InChI Key: WLAKUAILRGATSL-UHFFFAOYSA-N
• Exact Mass: 115.02335542
• Molecular Formula: C5H3F2N
• Molecular Weight: 115.08
• SMILES: C1=CN=C(C=C1F)F
• Topological: 12.9
• Monoisotopic Mass: 115.02335542
• Synonyms: 2,4-difluoropyridine, 34941-90-7, DTXSID00376499, DTXCID00327527, 680-722-6, 2,4-Difluoro-pyridine, MFCD04114162, Pyridine, 2,4-difluoro-, 2,4-bis(fluoranyl)pyridine, SCHEMBL948200, SCHEMBL1322641, SCHEMBL1697620, SCHEMBL4253170, WLAKUAILRGATSL-UHFFFAOYSA-N, AC-340, BBL100923, STL554717, AKOS005063485, CS-W011239, PB26122, SY024692, TS-01588, DB-005862, EN300-99859

2,4-Difluoropyridine serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly kinase inhibitors and antiviral agents. Its electron-deficient ring system facilitates regioselective functionalization in Pd-catalyzed cross-coupling reactions. The compound is also employed in liquid crystal material development and as a precursor for agricultural chemicals. Researchers value its stability under anhydrous conditions for organometallic transformations.

Safety and Hazards

GHS Hazard Statements

• H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (88.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (88.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.