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Atomfair 2,4-Dichloro-5-iodopyridine C5H2Cl2IN CAS 343781-49-7

2,4-Dichloro-5-iodopyridine (CAS No. 343781-49-7) is a high-purity halogenated pyridine derivative with the molecular formula C5H2Cl2IN . This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both chloro and iodo substituents on the pyridine ring, enables selective functionalization for the development of complex heterocyclic compounds. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a crystalline solid under inert packaging to maintain stability. Ideal for Suzuki couplings, nucleophilic substitutions, and metal-catalyzed cross-coupling reactions. Key Features: IUPAC Name: 2,4-dichloro-5-iodopyridine CAS: 343781-49-7 | EC: 866-406-2 Molecular Weight:…

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Description

2,4-Dichloro-5-iodopyridine (CAS No. 343781-49-7) is a high-purity halogenated pyridine derivative with the molecular formula C5H2Cl2IN. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both chloro and iodo substituents on the pyridine ring, enables selective functionalization for the development of complex heterocyclic compounds. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a crystalline solid under inert packaging to maintain stability. Ideal for Suzuki couplings, nucleophilic substitutions, and metal-catalyzed cross-coupling reactions.

Key Features:

  • IUPAC Name: 2,4-dichloro-5-iodopyridine
  • CAS: 343781-49-7 | EC: 866-406-2
  • Molecular Weight: 273.89 g/mol
  • Storage: 2-8°C under nitrogen
  • Hazard Codes: H302-H315-H319-H335

Properties

  • CAS Number: 343781-49-7
  • Complexity: 101
  • IUPAC Name: 2,4-dichloro-5-iodo-pyridine
  • InChI: InChI=1S/C5H2Cl2IN/c6-3-1-5(7)9-2-4(3)8/h1-2H
  • InChI Key: BXGGIBSWLOTEPO-UHFFFAOYSA-N
  • Exact Mass: 272.86090
  • Molecular Formula: C5H2Cl2IN
  • Molecular Weight: 273.88
  • SMILES: C1=C(C(=CN=C1Cl)I)Cl
  • Topological: 12.9
  • Monoisotopic Mass: 272.86090
  • Synonyms: 2,4-dichloro-5-iodopyridine, 343781-49-7, DTXSID80441518, DTXCID80392339, 866-406-2, MFCD09033755, 2,4-dichloro-5-iodo-pyridine, 5-Iodo-2,4-dichloropyridine, SCHEMBL16997464, BBL102011, STL555810, 2 pound not4-Dichloro-5-iodopyridine, AKOS015889462, CS-W021506, DS-18361, SY037731, DB-068978, F19994

Application

2,4-Dichloro-5-iodopyridine serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. Its reactivity at the 2, 4, and 5 positions allows for sequential modifications, making it valuable in constructing kinase inhibitors and antimicrobial agents. Researchers utilize this compound in palladium-catalyzed cross-coupling reactions to introduce pyridine motifs into complex molecules. It is also employed in material science for developing functionalized ligands in coordination chemistry.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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