Atomfair 2,3-dihydro-1H-isoindole hydrochloride C8H10ClN CAS 32372-82-0

2,3-Dihydro-1H-isoindole hydrochloride (CAS No. 32372-82-0) is a high-purity organic compound with the molecular formula C8H10ClN. This hydrochloride salt of isoindoline is a versatile building block in pharmaceutical and chemical synthesis, offering excellent reactivity for heterocyclic and nitrogen-containing frameworks. With a molecular weight of 155.63 g/mol, it appears as a white to off-white crystalline powder, soluble in water and polar organic solvents. Ideal for researchers, this product is rigorously tested for purity (typically ≥95% by HPLC or GC analysis) and is supplied in sealed containers to ensure stability. Suitable for use in medicinal chemistry, catalysis, and material science applications.

Description

2,3-Dihydro-1H-isoindole hydrochloride (CAS No. 32372-82-0) is a high-purity organic compound with the molecular formula C8H10ClN. This hydrochloride salt of isoindoline is a versatile building block in pharmaceutical and chemical synthesis, offering excellent reactivity for heterocyclic and nitrogen-containing frameworks. With a molecular weight of 155.63 g/mol, it appears as a white to off-white crystalline powder, soluble in water and polar organic solvents. Ideal for researchers, this product is rigorously tested for purity (typically ≥95% by HPLC or GC analysis) and is supplied in sealed containers to ensure stability. Suitable for use in medicinal chemistry, catalysis, and material science applications.

Properties

  • CAS Number: 32372-82-0
  • Complexity: 88.7
  • IUPAC Name: isoindoline;hydrochloride
  • InChI: InChI=1S/C8H9N.ClH/c1-2-4-8-6-9-5-7(8)3-1;/h1-4,9H,5-6H2;1H
  • InChI Key: NOVIRODZMIZUPA-UHFFFAOYSA-N
  • Exact Mass: 155.0501770
  • Molecular Formula: C8H10ClN
  • Molecular Weight: 155.62
  • SMILES: C1C2=CC=CC=C2CN1.Cl
  • Topological: 12
  • Monoisotopic Mass: 155.0501770
  • Synonyms: 2,3-dihydro-1H-isoindole hydrochloride, 675-776-2, isoindoline hydrochloride, 32372-82-0, 2,3-Dihydroisoindole hydrochloride, ISOINDOLINE HCL, Isoindoline, HCl, 2,3-dihydro-1H-isoindole;hydrochloride, MFCD03502377, 2,3-Dihydro-1H-isoindol hydrochloride, Isoindoline HCl salt, 1H-Isoindole, 2,3-dihydro-, hydrochloride, F1993-0036, 2,3-dihydro-1H-isoindole,hydrochloride, SCHEMBL4702076, DTXSID50487241, NOVIRODZMIZUPA-UHFFFAOYSA-N, BCP15681, CS-D1516, SC3601, AKOS015844749, GS-3911, SB66088, SY006502, I0958, EN300-70584, Z1263820391

Application

2,3-Dihydro-1H-isoindole hydrochloride serves as a key intermediate in the synthesis of bioactive compounds, including CNS-targeting drugs and heterocyclic scaffolds. It is utilized in pharmaceutical research for developing isoindoline-based inhibitors and ligands. This compound also finds applications in asymmetric catalysis and as a precursor for functionalized polymers. Its stability and reactivity make it valuable for exploratory organic synthesis.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (75%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (75%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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