Description

2,3-Difluoro-4-iodophenol (CAS No. 144292-40-0) is a high-purity halogenated phenol derivative with the molecular formula C₆H₃F₂IO. This compound is characterized by its unique substitution pattern, featuring two fluorine atoms at the 2- and 3-positions and an iodine atom at the 4-position of the phenolic ring. It is a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. The presence of both fluorine and iodine atoms enhances its reactivity, making it suitable for cross-coupling reactions, nucleophilic substitutions, and other transformations. Available in various quantities, this product is rigorously tested to ensure >98% purity (HPLC) and is supplied with comprehensive analytical data, including ¹H NMR, ¹³C NMR, and MS spectra. Store in a cool, dry place under inert conditions to maintain stability.

Properties

• CAS Number: 144292-40-0
• Complexity: 122
• IUPAC Name: 2,3-difluoro-4-iodo-phenol
• InChI: InChI=1S/C6H3F2IO/c7-5-3(9)1-2-4(10)6(5)8/h1-2,10H
• InChI Key: IXJVMKIJWFFXCR-UHFFFAOYSA-N
• Exact Mass: 255.91967
• Molecular Formula: C6H3F2IO
• Molecular Weight: 255.99
• SMILES: C1=CC(=C(C(=C1O)F)F)I
• Topological: 20.2
• Monoisotopic Mass: 255.91967
• Synonyms: 2,3-Difluoro-4-iodophenol, 144292-40-0, Phenol, 2,3-difluoro-4-iodo-, MFCD08741391, 4-IODO-2,3-DIFLUOROPHENOL, SCHEMBL232501, DTXSID60617653, IXJVMKIJWFFXCR-UHFFFAOYSA-N, BBL100637, SBB101653, STL554431, AKOS005254706, PS-10209, DB-030769

Application

2,3-Difluoro-4-iodophenol is widely used as a versatile building block in medicinal chemistry for the synthesis of fluorinated drug candidates. Its iodine moiety facilitates palladium-catalyzed cross-coupling reactions, such as Suzuki or Sonogashira reactions, to create complex aromatic systems. Researchers also employ it in the development of agrochemicals due to the bioactivity imparted by the fluorine substituents. Additionally, it serves as a precursor for advanced materials, including liquid crystals and OLED components, where halogenated phenols are critical for tuning electronic properties.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.