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Atomfair 2,3-Dichloropyridine C5H3Cl2N CAS 2402-77-9
2,3-Dichloropyridine (CAS No. 2402-77-9) is a high-purity halogenated pyridine derivative with the molecular formula C5H3Cl2N . This compound is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and material science research. Its structure features two chlorine atoms at the 2- and 3-positions of the pyridine ring, enabling selective functionalization for complex molecule construction. Available in >98% purity (GC), it is supplied as a clear to pale-yellow liquid or crystalline solid, stored under inert conditions to ensure stability. Ideal for nucleophilic substitution, cross-coupling reactions (e.g., Suzuki, Stille), and as a precursor for heterocyclic scaffolds. Suitable for HPLC, NMR,…
Description
2,3-Dichloropyridine (CAS No. 2402-77-9) is a high-purity halogenated pyridine derivative with the molecular formula C5H3Cl2N. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and material science research. Its structure features two chlorine atoms at the 2- and 3-positions of the pyridine ring, enabling selective functionalization for complex molecule construction. Available in >98% purity (GC), it is supplied as a clear to pale-yellow liquid or crystalline solid, stored under inert conditions to ensure stability. Ideal for nucleophilic substitution, cross-coupling reactions (e.g., Suzuki, Stille), and as a precursor for heterocyclic scaffolds. Suitable for HPLC, NMR, and LC-MS analysis. Handle with proper PPE due to potential irritant properties.
Properties
- CAS Number: 2402-77-9
- Complexity: 76.8
- IUPAC Name: 2,3-dichloropyridine
- InChI: InChI=1S/C5H3Cl2N/c6-4-2-1-3-8-5(4)7/h1-3H
- InChI Key: MAKFMOSBBNKPMS-UHFFFAOYSA-N
- Exact Mass: 146.9642545
- Molecular Formula: C5H3Cl2N
- Molecular Weight: 147.99
- SMILES: C1=CC(=C(N=C1)Cl)Cl
- Topological: 12.9
- Monoisotopic Mass: 146.9642545
- Synonyms: 2,3-DICHLOROPYRIDINE, Pyridine, 2,3-dichloro-, G8S8JY2HE2, NSC-298535, PYRIDINE,2,3-DICHLORO, DTXSID7051894, DTXCID5030456, 219-281-8, inchi=1/c5h3cl2n/c6-4-2-1-3-8-5(4)7/h1-3, makfmosbbnkpms-uhfffaoysa-n, 2402-77-9, 2,3-dichloro-pyridine, MFCD00006229, dichloropyridine, 2,3-Dichloropyridine(Monolabeled), Pyridine, dichloro-, CCRIS 1726, EINECS 219-281-8, NSC 298535, BRN 0109811, NSC298535, 2.3-dichloropyridine, Pyridine,3-dichloro-, 2,3-dichloro-pyridin, 2,3-dichloro pyridine, 2.3-dichloro-pyridine, 2, 3-Dichloropyridine, UNII-G8S8JY2HE2, WLN: T6NJ BG CG, EC 219-281-8, SCHEMBL41049, 5-20-05-00415 (Beilstein Handbook Reference), 2,3-Dichloropyridine, 99%, SCHEMBL229616, SCHEMBL405539, SCHEMBL791456, CHEMBL4635484, BCP23406, STR00483, FD9101, SBB086564, STL183288, AKOS000121081, AB00641, AC-5932, CS-W013307, FD00448, FG-0505, HY-W012591, BP-11476, DB-023843, D2906, NS00008053, EN300-23802, A15403, 2,3-Dichloropyridine, purum, >=97.0% (AT), AF-834/25002667, F0001-0821
Application
2,3-Dichloropyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and crop protection agents. Its dichloro-substituted pyridine core is leveraged in palladium-catalyzed cross-coupling reactions to construct biaryl systems. Researchers utilize it to develop ligands for catalysis and functional materials. In medicinal chemistry, it aids in creating kinase inhibitors and antimicrobial compounds. Also employed in electronic materials for its electron-withdrawing properties.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (99.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
- STOT SE 3 (99.1%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.
Disclaimer
Intended Use & Restrictions
This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.
- Strictly prohibited: Resale, repackaging, or formulation into commercial products.
- Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).
Patent & Regulatory Compliance
Certain molecules may be protected by active patents or regulatory restrictions.
- Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
- Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.
Liability Release
By purchasing, the buyer agrees to:
- Use this product only as permitted by law.
- Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.
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