Description

3-(Trifluoromethyl)-1H-pyridin-2-one (CAS No. 22245-83-6) is a high-purity fluorinated heterocyclic compound with the molecular formula C₆H₄F₃NO. This specialized chemical is designed for advanced research applications, particularly in pharmaceutical and agrochemical development. The presence of the trifluoromethyl group enhances its reactivity and metabolic stability, making it a valuable scaffold for drug discovery. Our product is synthesized under strict quality control measures, ensuring >98% purity by HPLC analysis. Suitable for use as a building block in medicinal chemistry, this compound is provided in sealed, light-resistant packaging to ensure stability. Researchers can rely on its consistent quality for synthesizing novel bioactive molecules, including kinase inhibitors and antimicrobial agents.

Properties

• CAS Number: 22245-83-6
• Complexity: 239
• IUPAC Name: 3-(trifluoromethyl)-1H-pyridin-2-one
• InChI: InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-10-5(4)11/h1-3H,(H,10,11)
• InChI Key: JHDCDEHVUADNKQ-UHFFFAOYSA-N
• Exact Mass: 163.02449824
• Molecular Formula: C6H4F3NO
• Molecular Weight: 163.10
• SMILES: C1=CNC(=O)C(=C1)C(F)(F)F
• Topological: 29.1
• Monoisotopic Mass: 163.02449824
• Synonyms: 3-(trifluoromethyl)pyridin-2-ol, 2(1H)-PYRIDINONE, 3-(TRIFLUOROMETHYL)-, 671-273-7, 948-667-5, 22245-83-6, 2-Hydroxy-3-Trifluoromethylpyridine, 2-Hydroxy-3-(trifluoromethyl)pyridine, 2-Hydroxy-3-Trifluoromethyl Pyridine, 3-(trifluoromethyl)-1H-pyridin-2-one, 3-(Trifluoromethyl)-2-pyridone, 3-(Trifluoromethyl)pyridin-2(1H)-one, MFCD00153194, 3-trifluoromethyl-pyridin-2-ol, Maybridge1_006338, 3-trifluoromethyl-pyridone, 3-(TRIFLUOROMETHYL)-2(1H)-PYRIDINONE, 3-trifluoromethyl-2-pyridinol, SCHEMBL908781, SCHEMBL909449, 3-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDIN-2-ONE, HTF (SSRE-021), SCHEMBL2305693, SCHEMBL6960811, SCHEMBL9901755, SCHEMBL9901898, HMS559I02, DTXSID80394934, 3-(Trifluoromethyl)-2-pyridinone, DEAQPLNBCHAGLL-UHFFFAOYSA-N, BCP22483, 2-hydroxy-3-trifluoromethyl-pyridine, BBL100581, CX1235, FD2043, SBB055713, STL554375, AKOS001434019, AKOS028108750, AB04092, CS-W002444, DS-0797, FS-1128, 2-hydroxy-3-(trifluoromethyl)-pyridine, AC-20524, SY012473, DB-006141, NS00067405, ST50950011, T2600, EN300-28545, 2-hydroxy-3-(trifluoromethyl)pyridine, AldrichCPR, Z235348047, 3-(Trifluoromethyl)pyridin-2-ol, 3-(Trifluoromethyl)pyridin-2(1H)-one

Application

3-(Trifluoromethyl)-1H-pyridin-2-one serves as a key intermediate in the synthesis of fluorinated pharmaceutical compounds. Its unique structure makes it valuable for developing kinase inhibitors targeting cancer pathways. The compound is also utilized in agrochemical research for creating novel pesticides with enhanced metabolic stability. Researchers employ this building block to modify pharmacokinetic properties of lead compounds in drug discovery programs.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (66.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.