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Atomfair 2-(Trifluoromethyl)benzeneboronic acid 2-TFMBA C7H6BF3O2

Description 2-(Trifluoromethyl)benzeneboronic acid (CAS No. 1423-27-4) is a high-purity boronic acid derivative with the molecular formula C7H6BF3O2, widely used in organic synthesis and pharmaceutical research. This compound, also known by its IUPAC name [2-(trifluoromethyl)phenyl]boronic acid , features a boronic acid functional group ortho to a trifluoromethyl substituent, enhancing its reactivity in Suzuki-Miyaura cross-coupling reactions. Its crystalline form ensures stability and ease of handling under inert conditions. Ideal for researchers, this reagent is rigorously tested for purity (typically ??95-98% by HPLC or NMR) and is supplied in moisture-resistant packaging to maintain integrity. Suitable for catalysis, ligand design, and medicinal chemistry applications.

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Description

Description

2-(Trifluoromethyl)benzeneboronic acid (CAS No. 1423-27-4) is a high-purity boronic acid derivative with the molecular formula C7H6BF3O2, widely used in organic synthesis and pharmaceutical research. This compound, also known by its IUPAC name [2-(trifluoromethyl)phenyl]boronic acid, features a boronic acid functional group ortho to a trifluoromethyl substituent, enhancing its reactivity in Suzuki-Miyaura cross-coupling reactions. Its crystalline form ensures stability and ease of handling under inert conditions. Ideal for researchers, this reagent is rigorously tested for purity (typically ??95-98% by HPLC or NMR) and is supplied in moisture-resistant packaging to maintain integrity. Suitable for catalysis, ligand design, and medicinal chemistry applications.

  • CAS No: 1423-27-4
  • Molecular Formula: C7H6BF3O2
  • Molecular Weight: 189.93
  • Exact Mass: 190.0412941
  • Monoisotopic Mass: 190.0412941
  • IUPAC Name: [2-(trifluoromethyl)phenyl]boronic acid
  • SMILES: B(C1=CC=CC=C1C(F)(F)F)(O)O
  • Synonyms: 2-Trifluoromethylphenylboronic acid, 2-(Trifluoromethyl)benzeneboronic acid, 640-203-7, 1423-27-4, 2-(Trifluoromethyl)phenylboronic acid

Application

2-(Trifluoromethyl)benzeneboronic acid is a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl compounds for pharmaceuticals and agrochemicals. Its trifluoromethyl group enhances lipophilicity and metabolic stability in drug discovery. The compound is also used in materials science for designing fluorinated organic frameworks. Researchers leverage its boronic acid moiety for sensor development and carbohydrate recognition studies.

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