Description

2-Nitrophenylhydrazine Hydrochloride (CAS No. 6293-87-4) is a high-purity chemical reagent widely utilized in organic synthesis and analytical chemistry applications. With the molecular formula C₆H₈ClN₃O₂, this compound serves as a critical derivatization agent for carbonyl compounds, facilitating their detection and quantification via HPLC and spectrophotometric methods. Its robust reactivity with aldehydes and ketones makes it indispensable in biochemical research, pharmaceutical development, and environmental testing. Available in crystalline form, our product undergoes stringent quality control to ensure ≥98% purity, meeting the rigorous demands of laboratory and industrial workflows. Store in a cool, dry place, protected from light and moisture to maintain stability.

Properties

• CAS Number: 6293-87-4
• Complexity: 145
• IUPAC Name: (2-nitrophenyl)hydrazine;hydrochloride
• InChI: InChI=1S/C6H7N3O2.ClH/c7-8-5-3-1-2-4-6(5)9(10)11;/h1-4,8H,7H2;1H
• InChI Key: XCUBVSAYUSFHNN-UHFFFAOYSA-N
• Exact Mass: 189.0305042
• Molecular Formula: C6H8ClN3O2
• Molecular Weight: 189.60
• SMILES: C1=CC=C(C(=C1)NN)[N+](=O)[O-].Cl
• Topological: 83.9
• Monoisotopic Mass: 189.0305042
• Synonyms: 2-Nitrophenylhydrazine Hydrochloride, DTXSID60971848, DTXCID901399340, 678-267-3, 6293-87-4, (2-nitrophenyl)hydrazine hydrochloride, 56413-75-3, o-Nitrophenylhydrazine hydrochloride, (2-nitrophenyl)hydrazine;hydrochloride, 2-Nitrophenylhydrazine, HCl, Hydrazine, (2-nitrophenyl)-, hydrochloride, (2-Nitrophenyl)hydrazine hydrochloride(1:x), (2-Nitrophenyl)hydrazine hydrochloride (Chunks or pellets), Hydrazine, (2-nitrophenyl)-, monohydrochloride, 2-NITROPHENYLHYDRAZINE HCL, MFCD00060205, ONPH, o-Nitrophenylhydrazine HCl, 2-Nitrophenyl hydrazine hcl, SCHEMBL210003, CCRIS 3138, NSC9184, GAA29387, NSC-9184, AKOS005256221, AC-7189, CS-W002278, DS-3386, (o-Nitrophenyl)hydrazine monohydrochloride, DB-021453, N0231, EN300-31716, F8889-5919

2-Nitrophenylhydrazine Hydrochloride is primarily employed as a derivatizing agent for carbonyl compounds (aldehydes and ketones) in HPLC and UV-Vis analysis, enhancing detection sensitivity. It is also used in organic synthesis to prepare hydrazone derivatives for structural elucidation studies. Researchers leverage its reactivity in pharmaceutical impurity profiling and environmental pollutant monitoring.

Safety and Hazards

GHS Hazard Statements

• H228 (66.7%): Flammable solid [Danger Flammable solids]
• H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (66.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (66.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (33.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P240, P241, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501

Hazard Classes and Categories

• Flam. Sol. 1 (66.7%)
• Acute Tox. 4 (66.7%)
• Acute Tox. 4 (66.7%)
• Skin Irrit. 2 (66.7%)
• Eye Irrit. 2A (66.7%)
• Acute Tox. 4 (66.7%)
• STOT SE 3 (33.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.