Description

2-Nitroaniline (CAS 88-74-4) is a high-purity aromatic amine compound with the molecular formula C₆H₆N₂O₂, widely utilized in organic synthesis and industrial applications. This yellow to orange crystalline powder exhibits a melting point of 71-73°C and is sparingly soluble in water but readily dissolves in organic solvents such as ethanol and acetone. As a nitro-substituted aniline derivative, it serves as a critical intermediate in the production of dyes, pigments, and pharmaceuticals. Our product is rigorously tested for purity (≥98%) and consistency, ensuring optimal performance in research and manufacturing processes. Proper handling precautions are advised due to its potential toxicity and irritant properties.

Properties

• CAS Number: 88-74-4
• Complexity: 132
• IUPAC Name: 2-nitroaniline
• InChI: InChI=1S/C6H6N2O2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H,7H2
• InChI Key: DPJCXCZTLWNFOH-UHFFFAOYSA-N
• LogP: log Kow = 1.85
• Exact Mass: 138.042927438
• Molecular Formula: C6H6N2O2
• Molecular Weight: 138.12
• SMILES: C1=CC=C(C(=C1)N)[N+](=O)[O-]
• Topological: 71.8
• Monoisotopic Mass: 138.042927438
• Physical Description: O-nitroaniline is an orange solid with a musty odor. Sinks and mixes slowly with water.
• Color/Form: Yellow-orange crystals from boiling water
• Odor: Musty
• Boiling Point: 543 °F at 760 mmHg
• Melting Point: 160.7 °F
• Flash Point: 335 °F
• Solubility: less than 1 mg/mL at 70.7 °F
• Density: 1.44 at 68 °F – Denser than water; will sink
• Vapor Density: 4.77 – Heavier than air; will sink
• Vapor Pressure: 1 mmHg at 219.2 °F ; <0.1 mmHg at 86 °F
• Henry’s Law Constant: Henry’s Law constant = 5.90X10-8 atm-cu m/mol at 25 °C
• Autoignition Temperature: 970 °F
• Heat of Combustion: -10,000 Btu/lb= -5,550 cal/g= -232×10+5 J/kg
• Dissociation Constants: pKa = -0.28
• Synonyms: 2-NITROANILINE, o-Nitroaniline, 2-Nitrobenzenamine, Benzenamine, 2-nitro-, Diazo Fast Orange GR, 2-Nitro-phenylamine, ortho-nitroaniline, Natasol Fast Orange GR Salt, NSC 9796, CI Azoic Diazo Component 6, CCRIS 2317, 2-NITRO-ANILINE, DTXSID1025726, o-Nitranilin, HSDB 1132, CI 37025, 2-nitrophenylamine, EINECS 201-855-4, 2-Nitro-benzeneamine, AI3-02916, UNII-2519U0541L, NSC-9796, NITROANILINE, O-, O-NITROANILINE [MI], 2-NITROANILINE [HSDB], DTXCID905726, EC 201-855-4, oNitraniline, oNitroaniline, Aniline, onitro, 2Nitrobenzenamine, oAminonitrobenzene, 2Aminonitrobenzene, 1Amino2nitrobenzene, Benzenamine, 2nitro, dpjcxcztlwnfoh-uhfffaoysa-n, inchi=1/c6h6n2o2/c7-5-3-1-2-4-6(5)8(9)10/h1-4h,7h, un1661, 88-74-4, o-Nitraniline, 1-Amino-2-nitrobenzene, Fast Orange GR Base, Devol Orange B, Orange GRS Salt, o-Aminonitrobenzene, 2-Aminonitrobenzene, Aniline, o-nitro-, Fast Orange O Base, Fast Orange O Salt, Devol Orange Salt B, Orthonitroaniline, Fast Orange Base GR, Fast Orange Base JR, Fast Orange GR Salt, Fast Orange Salt GR, Fast Orange Salt JR, Orange Base Ciba II, Orange Base Irga II, Orange Salt Ciba II, Orange Salt Irga II, Azoene Fast Orange GR Salt, Azofix Orange GR Salt, Azogene Fast Orange GR, Hindasol Orange GR Salt, Azoic Diazo Component 6, Azoene Fast Orange GR Base, Hiltonil Fast Orange GR Base, Hiltosal Fast Orange GR Salt, Brentamine Fast Orange GR Base, Brentamine Fast Orange GR Salt, C.I. Azoic Diazo Component 6, C.I. 37025, Aniline, 2-nitro-, ONA, 2519U0541L, o-nitro aniline, CAS-88-74-4, 2nitroaniline, o-nitro-aniline, 2-nitro aniline, 2-nitro-anilin, MFCD00007687, (2-nitrophenyl)-amine, 1-Nitro-2-aminobenzene, 2-Nitroaniline, 98%, 2-Nitroaniline, 99%, 2-Nitroaniline-al-14c, (2-nitro-phenyl)-amine, WLN: ZR BNW, SCHEMBL6000, SCHEMBL301032, CHEMBL274009, SCHEMBL1028967, SCHEMBL1036583, SCHEMBL2783828, SCHEMBL6129444, SCHEMBL10503974, SCHEMBL11911292, NSC9796, BCP05324, STR00840, Tox21_202371, Tox21_303292, BDBM50554334, SBB040877, STL140693, AKOS000119116, o-Nitroaniline [UN1661] [Poison], NCGC00091373-01, NCGC00091373-02, NCGC00257171-01, NCGC00259920-01, BP-21264, DB-057102, N0118, NS00003098, ST45255269, EN300-17394, D97708, Q2590230, Z56924541, F2190-0432, 38500-40-2

Application

2-Nitroaniline is primarily employed as a precursor in the synthesis of azo dyes and pigments, particularly for textile and ink applications. It also functions as an intermediate in pharmaceutical manufacturing, contributing to the development of antimicrobial and anti-inflammatory agents. Researchers utilize this compound in organic reactions, including diazotization and coupling processes, to produce complex aromatic structures.

Safety and Hazards

GHS Hazard Statements

• H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]
• H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P273, P391, and P501

Hazard Classes and Categories

• Acute Tox. 3 (97.4%)
• Acute Tox. 3 (99.1%)
• Acute Tox. 3 (97.4%)
• STOT RE 2 (99.1%)
• Aquatic Chronic 3 (99.6%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.