Description

2-Methoxypyridin-4-amine (CAS: 20265-39-8) is a high-purity organic compound with the molecular formula C₆H₈N₂O, widely utilized in pharmaceutical research, agrochemical development, and material science applications. This heterocyclic amine features a methoxy substituent at the 2-position of the pyridine ring, enhancing its reactivity and utility as a versatile intermediate in synthetic chemistry. With exceptional purity and stability, it is ideal for nucleophilic substitution reactions, cross-coupling methodologies, and as a precursor for bioactive molecules. Packaged under inert conditions to ensure longevity, this product is rigorously tested via HPLC, GC-MS, and NMR to meet stringent industry standards. Suitable for laboratory-scale synthesis and industrial-scale production, it is available in quantities ranging from grams to kilograms.

Properties

• CAS Number: 20265-39-8
• Complexity: 87.1
• IUPAC Name: 2-methoxypyridin-4-amine
• InChI: InChI=1S/C6H8N2O/c1-9-6-4-5(7)2-3-8-6/h2-4H,1H3,(H2,7,8)
• InChI Key: SVEQHRSELNPKJJ-UHFFFAOYSA-N
• Exact Mass: 124.063662883
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.14
• SMILES: COC1=NC=CC(=C1)N
• Topological: 48.1
• Monoisotopic Mass: 124.063662883
• Synonyms: 4-Amino-2-methoxypyridine, 20265-39-8, 2-methoxypyridin-4-amine, DTXSID50942385, DTXCID701370788, 674-597-7, 2-Methoxy-pyridin-4-ylamine, 2-Methoxy- 4-Aminopyridine, MFCD06738657, 4-PYRIDINAMINE, 2-METHOXY-, 2-Methoxy-4-aminopyridine, 2-METHOXY-4-PYRIDINAMINE, NSC133109, 2-methoxy-4-pyridylamine, 2-Methoxypyridin-4yl-amine, 4-amino-2-methoxy-pyridine, SCHEMBL68300, pyridine, 4-amino-2-methoxy-, AEA11458, CS-D0771, SBB051798, AKOS005257298, AC-4386, FA33029, NSC-133109, PB20942, PS-4733, 2-Methoxy-pyridin-4-ylamine, AldrichCPR, SY005153, DB-006181, A2543, EN300-97036, AC-907/34117057, (4-aminopyridin-2-yl)methanol; 4-amino-2-pyridilcarbinol

2-Methoxypyridin-4-amine serves as a key building block in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antimicrobial agents. Its methoxy and amino functional groups enable facile derivatization for drug discovery pipelines. Researchers also employ it in agrochemical formulations to create novel pesticidal and herbicidal agents. Additionally, it is used in materials science for designing functionalized polymers and ligands for catalytic systems.

Safety and Hazards

GHS Hazard Statements

• H302 (90.7%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (90.7%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (97.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.