Description

(2-Hydroxyquinolin-3-yl)boronic acid (CAS No. 1101864-58-7) is a high-purity boronic acid derivative with the molecular formula C₉H₈BNO₃. This compound, also known by its IUPAC name (2-oxo-1H-quinolin-3-yl)boronic acid, is a valuable building block in organic synthesis and pharmaceutical research. Its unique quinoline scaffold coupled with the boronic acid functional group makes it an essential reagent for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex molecular architectures.

Our product is rigorously tested for quality, ensuring ≥95% purity by HPLC, and is supplied as a fine, off-white to light yellow crystalline powder. It is packaged under inert conditions to maintain stability and is ideal for use in medicinal chemistry, materials science, and catalysis research. Store in a cool, dry place, protected from moisture and light to preserve its reactivity.

Properties

• CAS Number: 1101864-58-7
• Complexity: 277
• IUPAC Name: (2-oxo-1H-quinolin-3-yl)boronic acid
• InChI: InChI=1S/C9H8BNO3/c12-9-7(10(13)14)5-6-3-1-2-4-8(6)11-9/h1-5,13-14H,(H,11,12)
• InChI Key: RIRFRJDLNNSOJT-UHFFFAOYSA-N
• Exact Mass: 189.0597233
• Molecular Formula: C9H8BNO3
• Molecular Weight: 188.98
• SMILES: B(C1=CC2=CC=CC=C2NC1=O)(O)O
• Topological: 69.6
• Monoisotopic Mass: 189.0597233
• Synonyms: (2-Hydroxyquinolin-3-yl)boronic acid, 896-808-3, 1101864-58-7, 2-HYDROXYQUINOLIN-3-YLBORONIC ACID, (2-oxo-1H-quinolin-3-yl)boronic acid, (2-oxo-1,2-dihydroquinolin-3-yl)boronic acid, (2-Hydroxyquinolin-3-yl)boronicacid, SCHEMBL15876680, DTXSID10677803, RIRFRJDLNNSOJT-UHFFFAOYSA-N, MFCD12964549, AKOS006304349, AB57829, AS-55684, DB-059982, CS-0060669, W17048, EN300-2151817, B-(1,2-dihydro-2-oxo-3-quinolinyl)Boronic acid, Z1198276711

Application

(2-Hydroxyquinolin-3-yl)boronic acid is widely used as a key intermediate in the synthesis of bioactive quinoline derivatives, particularly in pharmaceutical research for drug discovery. It serves as a versatile substrate in palladium-catalyzed cross-coupling reactions to construct complex heterocyclic frameworks. Researchers also utilize it in the development of fluorescent probes and sensors due to its inherent photophysical properties.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.