Description

2-Hydroxy-2-phenylacetohydrazide (CAS No. 2443-66-5) is a high-purity organic compound with the molecular formula C₈H₁₀N₂O₂. This white to off-white crystalline powder is a derivative of mandelic acid and is widely utilized in pharmaceutical research, organic synthesis, and biochemical applications. Its IUPAC name, 2-hydroxy-2-phenylacetohydrazide, reflects its structural composition, featuring a hydroxy-phenylacetamide core with a hydrazide functional group. Ideal for researchers and scientists, this compound is rigorously tested for quality, ensuring consistent performance in synthetic and analytical workflows. Available in various packaging options to suit laboratory needs, it is stored under controlled conditions to maintain stability and purity.

Properties

• CAS Number: 2443-66-5
• Complexity: 155
• IUPAC Name: 2-hydroxy-2-phenyl-acetohydrazide
• InChI: InChI=1S/C8H10N2O2/c9-10-8(12)7(11)6-4-2-1-3-5-6/h1-5,7,11H,9H2,(H,10,12)
• InChI Key: FWTGUGVETHVGTL-UHFFFAOYSA-N
• Exact Mass: 166.074227566
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.18
• SMILES: C1=CC=C(C=C1)C(C(=O)NN)O
• Topological: 75.4
• Monoisotopic Mass: 166.074227566
• Synonyms: 2-Hydroxy-2-phenylacetohydrazide, Hydroxy(phenyl)acetic acid hydrazide, 674-144-3, 2443-66-5, Mandelic acid hydrazide, Mandelic acid, hydrazide, Mandelhydrazide, Mandelhydrazine, 2-???-1-phenylethan-1-ol, mandelic hydrazide, Mandelohydrazide, MFCD21332895, Hydroxy-phenyl-acetic acid hydrazide, MFCD00038133, TimTec1_001774, Hydroxy(phenyl)acetohydrazide, Oprea1_383456, CHEMBL338836, SCHEMBL2978269, DTXSID80947303, 2-hydroxy-2-phenyl-acetohydrazide, HMS1539A14, 2-Hydroxy-2-phenylacetohydrazide #, ALBB-001061, SBB007729, STK033310, AKOS000295918, AKOS016050373, SB44850, SB85941, 2-Hydroxy-2-phenylethanehydrazonic acid, DL-Hydroxy(phenyl)acetic acid hydrazide, NCGC00340609-01, AS-61178, DA-07753, ST025733, SY017161, CS-0130077, D94755, AB01331677-02, EN300-5030612, AN-068/40184273

Application

2-Hydroxy-2-phenylacetohydrazide is primarily used as an intermediate in the synthesis of pharmaceuticals and bioactive compounds. Its hydrazide moiety makes it valuable for constructing heterocyclic frameworks in medicinal chemistry. Researchers also employ it in the development of novel chelating agents and as a precursor for catalysts. Additionally, it finds applications in biochemical studies related to enzyme inhibition and receptor binding assays.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.