Description

Description

2-Fluorothiophenol (CAS No. 2557-78-0) is a specialized organosulfur compound with the molecular formula C₆H₅FS. This high-purity reagent, also known as 2-fluorobenzenethiol, is widely utilized in synthetic organic chemistry, pharmaceutical research, and material science applications. The compound features a fluorine substituent at the ortho position of the thiophenol ring, enhancing its reactivity in nucleophilic aromatic substitution and metal-catalyzed coupling reactions.

Our 2-Fluorothiophenol is rigorously tested to meet the highest standards (??98% purity by GC), ensuring optimal performance in sensitive reactions. It is available in secure, light-resistant packaging under inert atmosphere to prevent oxidation. Ideal for use as a building block in heterocyclic synthesis, ligand design, and agrochemical intermediates.

Key Specifications:
– CAS: 2557-78-0
– Molecular Weight: 128.17 g/mol
– Appearance: Colorless to pale yellow liquid
– Density: 1.21 g/cm³ (predicted)
– Storage: 2-8??C under nitrogen
– Hazard Codes: Toxic (T), Corrosive (C)

Application

2-Fluorothiophenol serves as a versatile precursor in pharmaceutical synthesis, particularly for introducing fluorine-containing arylthio groups into target molecules. It is employed in palladium-catalyzed cross-coupling reactions to construct biaryl thioethers with enhanced metabolic stability. Researchers utilize this compound to develop novel PET radiotracers due to the favorable nuclear properties of fluorine-18. In materials science, it acts as a surface modifier for nanoparticles and a monomer for conductive polymers.

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