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Atomfair 2-Fluoropyridine C5H4FN CAS 372-48-5

2-Fluoropyridine (CAS No. 372-48-5) is a high-purity fluorinated heterocyclic compound with the molecular formula C5H4FN . This versatile building block is widely utilized in pharmaceutical, agrochemical, and materials science research due to its reactive fluorine substituent on the pyridine ring. Our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed, nitrogen-purged ampoules to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for more complex fluorinated scaffolds. Available in quantities ranging from 1g to 1kg with optional custom packaging. IUPAC Name: 2-fluoropyridine Synonyms: PYRIDINE, 2-FLUORO-; CCRIS 1725; AI3-28562; NSC 5077 Storage:…

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Description

2-Fluoropyridine (CAS No. 372-48-5) is a high-purity fluorinated heterocyclic compound with the molecular formula C5H4FN. This versatile building block is widely utilized in pharmaceutical, agrochemical, and materials science research due to its reactive fluorine substituent on the pyridine ring. Our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed, nitrogen-purged ampoules to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for more complex fluorinated scaffolds. Available in quantities ranging from 1g to 1kg with optional custom packaging.

  • IUPAC Name: 2-fluoropyridine
  • Synonyms: PYRIDINE, 2-FLUORO-; CCRIS 1725; AI3-28562; NSC 5077
  • Storage: Store under inert atmosphere at 2-8°C
  • Hazard Codes: F, Xn

Properties

  • CAS Number: 372-48-5
  • Complexity: 56
  • IUPAC Name: 2-fluoropyridine
  • InChI: InChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H
  • InChI Key: MTAODLNXWYIKSO-UHFFFAOYSA-N
  • Exact Mass: 97.032777294
  • Molecular Formula: C5H4FN
  • Molecular Weight: 97.09
  • SMILES: C1=CC=NC(=C1)F
  • Topological: 12.9
  • Monoisotopic Mass: 97.032777294
  • Physical Description: Clear dark brown liquid;
  • Vapor Pressure: 26.6 [mmHg]
  • Synonyms: 2-Fluoropyridine, PYRIDINE, 2-FLUORO-, CCRIS 1725, AI3-28562, NSC 5077, EINECS 206-757-5, BRN 0001515, DTXSID70190689, 5-20-05-00397 (Beilstein Handbook Reference), Pyridine, 2fluoro, DTXCID60113180, 206-757-5, inchi=1/c5h4fn/c6-5-3-1-2-4-7-5/h1-4, mtaodlnxwyikso-uhfffaoysa-n, un1993, 372-48-5, Pyridine, fluoro-, MFCD00006224, WKQ4JPY48S, NSC-5077, o-fluoropyridine, 2-Fluoropyridine; 2-Pyridyl Fluoride; NSC 5077;, fluoropyridine, 2Fluoropyridine, 2-fluoro-pyridine, 2-fluoranylpyridine, 2-Pyridyl fluoride, 2-Fluoro-pyridinium, 2-Fluoropyridine #, UNII-WKQ4JPY48S, 2-Fluoropyridine, 98%, SCHEMBL27545, SCHEMBL73118, SCHEMBL76868, SCHEMBL128813, SCHEMBL229752, SCHEMBL410501, SCHEMBL1287826, SCHEMBL2209903, SCHEMBL3615265, CHEMBL1162360, NSC5077, BCP23233, BBL010032, SBB062911, STK801408, AKOS000119365, AC-7018, CS-W011339, GS-6805, SB52269, BP-13083, DB-023956, DB-025029, F0217, NS00042189, EN300-20457, P16538, A823583, F0001-1073

Application

2-Fluoropyridine serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of kinase inhibitors and CNS-active compounds. The fluorine atom’s strong electron-withdrawing properties make this compound valuable for modifying electronic characteristics in material science applications. Researchers also employ it as a precursor for radiofluorination in PET tracer development.

Safety and Hazards

GHS Hazard Statements

  • H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (98%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

  • Flam. Liq. 3 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (98%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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