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Atomfair 2-Fluoropyridine-5-carbonyl chloride C6H3ClFNO

Description 2-Fluoropyridine-5-carbonyl chloride (CAS No. 65352-94-5) is a high-purity fluorinated pyridine derivative with the molecular formula C6H3ClFNO . This reactive acyl chloride is a versatile building block in organic synthesis, particularly for the introduction of the 6-fluoronicotinoyl moiety. The compound is characterized by its pale to colorless appearance and is typically supplied as a neat liquid or solution. With a molecular weight of 159.54 g/mol, it offers excellent reactivity for nucleophilic substitution reactions. Suitable for use under inert atmosphere, this product is ideal for pharmaceutical intermediates, agrochemical synthesis, and materials science applications. Store in tightly sealed containers under dry, cool…

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Description

Description

2-Fluoropyridine-5-carbonyl chloride (CAS No. 65352-94-5) is a high-purity fluorinated pyridine derivative with the molecular formula C6H3ClFNO. This reactive acyl chloride is a versatile building block in organic synthesis, particularly for the introduction of the 6-fluoronicotinoyl moiety. The compound is characterized by its pale to colorless appearance and is typically supplied as a neat liquid or solution. With a molecular weight of 159.54 g/mol, it offers excellent reactivity for nucleophilic substitution reactions. Suitable for use under inert atmosphere, this product is ideal for pharmaceutical intermediates, agrochemical synthesis, and materials science applications. Store in tightly sealed containers under dry, cool conditions to maintain stability.

  • CAS No: 65352-94-5
  • Molecular Formula: C6H3ClFNO
  • Molecular Weight: 159.54
  • Exact Mass: 158.9887196
  • Monoisotopic Mass: 158.9887196
  • IUPAC Name: 6-fluoropyridine-3-carbonyl chloride
  • SMILES: C1=CC(=NC=C1C(=O)Cl)F
  • Synonyms: 2-Fluoropyridine-5-carbonyl chloride, 687-741-9, 65352-94-5, 6-fluoropyridine-3-carbonyl chloride, 6-fluoronicotinoyl chloride

Application

2-Fluoropyridine-5-carbonyl chloride serves as a key intermediate in the synthesis of fluorinated pyridine derivatives with applications in pharmaceutical research. It is particularly valuable in the preparation of active pharmaceutical ingredients (APIs) and agrochemicals. The compound’s reactivity makes it suitable for amide bond formation in peptide mimetics and enzyme inhibitors. Researchers also utilize it in material science for creating specialized fluorinated polymers.

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