Description

(2-Fluorophenyl)hydrazine Hydrochloride (CAS No. 2924-15-4) is a high-purity organic compound with the molecular formula C₆H₈ClFN₂. This white to off-white crystalline powder is a valuable hydrazine derivative widely used in pharmaceutical synthesis, agrochemical research, and organic chemistry applications. With a molecular weight of 162.59 g/mol, it offers excellent reactivity for the preparation of heterocyclic compounds, including indoles, pyrazoles, and other nitrogen-containing scaffolds. The compound is packaged under inert conditions to ensure stability and is supplied with comprehensive analytical data (HPLC, NMR, MS) to guarantee quality for demanding research applications. Store in a cool, dry place away from light and oxidizing agents.

Properties

• CAS Number: 2924-15-4
• Complexity: 87.1
• IUPAC Name: (2-fluorophenyl)hydrazine;hydrochloride
• InChI: InChI=1S/C6H7FN2.ClH/c7-5-3-1-2-4-6(5)9-8;/h1-4,9H,8H2;1H
• InChI Key: VFZYLSYYMHFPSY-UHFFFAOYSA-N
• Exact Mass: 162.0360041
• Molecular Formula: C6H8ClFN2
• Molecular Weight: 162.59
• SMILES: C1=CC=C(C(=C1)NN)F.Cl
• Topological: 38.1
• Monoisotopic Mass: 162.0360041
• Synonyms: 2-Fluorophenylhydrazine hydrochloride, 2924-15-4, (2-fluorophenyl)hydrazine Hydrochloride, 2-Fluorophenylhydrazine HCl, MFCD00012927, Hydrazine, (2-fluorophenyl)-, hydrochloride (1:1), o-fluorophenylhydrazine hydrochloride, (2-fluorophenyl)hydrazine;hydrochloride, 1-(2-fluorophenyl)hydrazine hydrochloride, (2-Fluorophenyl)hydrazine, HCl, 2-fluorophenylhydrazinehydrochloride, Hydrazine, (2-fluorophenyl)-, monohydrochloride, SCHEMBL304797, 2-fluorophenylhydrazine, chloride, DTXSID00951846, NSC158012, SBB063993, (2-fluorophenyl)hydrazineHydrochloride, 2-fluoro-phenylhydrazine hydrochloride, 2-fluorophenyl hydrazine hydrochloride, AKOS005254514, 2-fluoro-phenyl-hydrazine hydrochloride, CS-W016106, GS-6787, NSC-158012, SB76538, (2-Fluorophenyl)hydrazine xhydrochloride, 40594-36-3, AC-16606, BP-10020, SY022145, (2-fluoro-phenyl)-hydrazine, hydrochloride, 2-Fluorophenylhydrazine hydrochloride, 97%, DB-021139, F0368, NS00048304, ST50824830, EN300-34689, (2-Fluorophenyl)hydrazine–hydrogen chloride (1/1), F0001-0910, Z220383458

(2-Fluorophenyl)hydrazine Hydrochloride serves as a key intermediate in the synthesis of fluorinated pharmaceuticals and bioactive molecules. Researchers utilize it for constructing indole derivatives via Fischer indole synthesis, important in drug discovery. The compound is also employed in the development of dyes, corrosion inhibitors, and coordination chemistry ligands. Its fluorophenyl group enhances metabolic stability in medicinal chemistry applications.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• Acute Tox. 4 (100%)
• STOT SE 3 (100%)

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