Description

Description

2-Fluoroanisole (CAS No. 321-28-8) is a high-purity fluorinated aromatic compound with the molecular formula C₇H₇FO and IUPAC name 1-fluoro-2-methoxybenzene. This specialty chemical is rigorously synthesized and purified to meet the stringent demands of pharmaceutical, agrochemical, and materials science research. Its unique structural features, combining an electron-donating methoxy group with an electron-withdrawing fluorine atom, make it a valuable building block for advanced synthetic applications.

Available in sealed glass ampules or bulk packaging under inert atmosphere to ensure stability, our 2-Fluoroanisole is characterized by GC-MS, ¹H/¹³C NMR, and elemental analysis to guarantee >98% purity (GC). The product is supplied with comprehensive analytical documentation including MSDS, Certificate of Analysis, and technical data sheets.

Key applications include use as:

• Precursor in transition metal-catalyzed cross-coupling reactions
• Intermediate for fluorinated liquid crystals and OLED materials
• Building block for bioactive molecule synthesis

Synonyms: 2-Fluoroanisole, 1-fluoro-2-methoxybenzene, EINECS 206-284-4, DTXSID50185891, NSC 10339

Application

2-Fluoroanisole serves as a versatile intermediate in organic synthesis, particularly in the preparation of fluorinated pharmaceuticals where its methoxy group can be further functionalized. The compound finds use in materials science for developing fluorinated liquid crystals with tailored dielectric properties. Researchers also employ it as a model substrate for studying electrophilic aromatic substitution reactions in fluorinated arenes.

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