Description

2-Fluoro-N-methoxy-N-methylbenzamide (CAS No. 198967-24-7) is a high-purity fluorinated benzamide derivative with the molecular formula C₉H₁₀FNO₂. This compound is characterized by its unique structural features, including a fluorine substituent at the 2-position of the benzamide ring and a methoxy-N-methyl group on the amide nitrogen. It is an important intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. The compound is supplied as a white to off-white crystalline powder with a purity of ≥95% (HPLC), ensuring consistency for research and industrial applications. Proper storage conditions (2-8°C, under inert atmosphere) are recommended to maintain stability. Available in various packaging options (100mg, 1g, 10g, 100g) to suit laboratory-scale and bulk requirements.

Properties

• CAS Number: 198967-24-7
• Complexity: 186
• IUPAC Name: 2-fluoro-N-methoxy-N-methyl-benzamide
• InChI: InChI=1S/C9H10FNO2/c1-11(13-2)9(12)7-5-3-4-6-8(7)10/h3-6H,1-2H3
• InChI Key: WWEPCBKULBKDCS-UHFFFAOYSA-N
• Exact Mass: 183.06955672
• Molecular Formula: C9H10FNO2
• Molecular Weight: 183.18
• SMILES: CN(C(=O)C1=CC=CC=C1F)OC
• Topological: 29.5
• Monoisotopic Mass: 183.06955672
• Synonyms: 2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE, 198967-24-7, DTXSID20593080, DTXCID80543844, 856-920-5, Benzamide, 2-fluoro-N-methoxy-N-methyl-, MFCD02684304, 2-fluoro-N-methoxy-N-methyl-benzamide, N-Methoxy-N-methyl-2-fluorobenzamide, SCHEMBL257659, WWEPCBKULBKDCS-UHFFFAOYSA-N, AKOS008953006, AS-10025, SY115940, CS-0042683, EN300-244592, W16958, Z54739602

Application

2-Fluoro-N-methoxy-N-methylbenzamide is primarily used as a versatile building block in medicinal chemistry for the synthesis of fluorinated drug candidates. Its reactive amide moiety makes it valuable for cross-coupling reactions and as a precursor for heterocyclic compounds. Researchers also employ this compound in the development of enzyme inhibitors and receptor modulators due to its fluorine-enhanced binding properties. Additionally, it finds application in material science for creating fluorinated polymers with enhanced stability.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• Acute Tox. 4 (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.