Description

Description

2-Fluoro-6-(trifluoromethyl)benzaldehyde (CAS No. 60611-24-7) is a high-purity fluorinated aromatic aldehyde with the molecular formula C₈H₄F₄O. This compound is characterized by its unique trifluoromethyl and fluoro substituents on the benzaldehyde backbone, making it a versatile intermediate in organic synthesis and pharmaceutical research. Its IUPAC name is 2-fluoro-6-(trifluoromethyl)benzaldehyde, and it is supplied as a clear to pale yellow liquid with a distinct aromatic odor. Suitable for use in nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for fluorinated heterocycles, this reagent is rigorously tested for purity (typically ??95% by GC) and stability under recommended storage conditions (2-8??C under inert atmosphere). Ideal for researchers in medicinal chemistry, agrochemical development, and materials science.

Application

2-Fluoro-6-(trifluoromethyl)benzaldehyde is a key building block in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its electron-withdrawing substituents. It serves as a precursor for bioactive molecules, including protease inhibitors and kinase modulators. The compound is also used in materials science to develop fluorinated liquid crystals and polymers with enhanced thermal stability. Its reactivity in Pd-catalyzed cross-coupling reactions makes it valuable for constructing complex aromatic systems.

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