Description

2-Ethoxypyridine (CAS No. 14529-53-4) is a high-purity organic compound with the molecular formula C₇H₉NO. This clear to pale yellow liquid is a versatile pyridine derivative, widely used as a building block in pharmaceutical synthesis, agrochemical production, and specialty chemical research. With a boiling point of approximately 180-182°C and a density of ~1.02 g/cm³, this reagent offers excellent solubility in common organic solvents while being sparingly soluble in water. Our product is rigorously tested to ensure ≥98% purity (GC), making it ideal for sensitive applications. Supplied in amber glass bottles under inert atmosphere to ensure stability, this compound is a valuable tool for researchers working on heterocyclic chemistry, ligand design, and nucleophilic substitution reactions.

Properties

• CAS Number: 14529-53-4
• Complexity: 75.3
• IUPAC Name: 2-ethoxypyridine
• InChI: InChI=1S/C7H9NO/c1-2-9-7-5-3-4-6-8-7/h3-6H,2H2,1H3
• InChI Key: LISKAOIANGDBTB-UHFFFAOYSA-N
• Exact Mass: 123.068413911
• Molecular Formula: C7H9NO
• Molecular Weight: 123.15
• SMILES: CCOC1=CC=CC=N1
• Topological: 22.1
• Monoisotopic Mass: 123.068413911
• Synonyms: 2-Ethoxypyridine, 14529-53-4, Pyridine, 2-ethoxy-, 4G3BKY7JKQ, EINECS 238-553-7, AI3-60422, DTXSID70162967, DTXCID0085458, 238-553-7, inchi=1/c7h9no/c1-2-9-7-5-3-4-6-8-7/h3-6h,2h2,1h, liskaoiangdbtb-uhfffaoysa-n, MFCD00023464, 2-Ethoxy-pyridine, ethyl 2-pyridinyl ether, UNII-4G3BKY7JKQ, SCHEMBL128768, SCHEMBL129035, SCHEMBL129417, SCHEMBL131609, SCHEMBL152133, SCHEMBL449878, SCHEMBL452905, SCHEMBL3186860, SCHEMBL6203272, CHEMBL3274301, AKOS005258151, CS-W017767, SB52293, AC-23102, AS-31090, SY017181, DB-003894, E0870, NS00024725, ST50409816, AC-907/25014179

Application

2-Ethoxypyridine serves as a key intermediate in the synthesis of complex pharmaceutical compounds, particularly those requiring pyridine-based scaffolds. In material science, it functions as a precursor for creating specialized ligands in coordination chemistry and catalysis. The ethoxy group’s reactivity makes this compound valuable for developing novel agrochemicals and fine chemicals through nucleophilic aromatic substitution reactions.

Safety and Hazards

GHS Hazard Statements

• H226 (11.4%): Flammable liquid and vapor [Warning Flammable liquids]
• H302 (88.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (88.6%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (11.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (11.4%)
• Acute Tox. 4 (88.6%)
• Skin Irrit. 2 (100%)
• Eye Dam. 1 (88.6%)
• Eye Irrit. 2 (11.4%)
• STOT SE 3 (97.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.