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Atomfair 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine C14H20BNO2 CAS 893567-09-4

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 893567-09-4) is a high-purity boronic ester derivative, extensively utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C14H20BNO2, features a cyclopropyl-substituted pyridine core coupled with a pinacol boronate ester group, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane ring ensures excellent handling and storage properties under inert conditions. Ideal for researchers developing novel heterocyclic compounds, this reagent is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring reliable performance in synthetic applications. Packaged under argon to prevent degradation, it is a must-have for medicinal chemistry and materials science laboratories.

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Description

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 893567-09-4) is a high-purity boronic ester derivative, extensively utilized in organic synthesis and pharmaceutical research. This compound, with the molecular formula C14H20BNO2, features a cyclopropyl-substituted pyridine core coupled with a pinacol boronate ester group, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane ring ensures excellent handling and storage properties under inert conditions. Ideal for researchers developing novel heterocyclic compounds, this reagent is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring reliable performance in synthetic applications. Packaged under argon to prevent degradation, it is a must-have for medicinal chemistry and materials science laboratories.

Properties

  • CAS Number: 893567-09-4
  • Complexity: 312
  • IUPAC Name: 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • InChI: InChI=1S/C14H20BNO2/c1-13(2)14(3,4)18-15(17-13)11-7-8-12(16-9-11)10-5-6-10/h7-10H,5-6H2,1-4H3
  • InChI Key: XJHHJKRQUDXIKL-UHFFFAOYSA-N
  • Exact Mass: 245.1587090
  • Molecular Formula: C14H20BNO2
  • Molecular Weight: 245.13
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)C3CC3
  • Topological: 31.4
  • Monoisotopic Mass: 245.1587090
  • Synonyms: 893567-09-4, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 6-Cyclopropylpyridine-3-boronic acid pinacol ester, MFCD09952039, 2-Cyclopropyl-5-pyridinyl boronic acid pinacol ester, 6-Cyclopropylpyridine-3-boronicacidpinacolester, 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER, SCHEMBL196887, DTXSID40671339, XJHHJKRQUDXIKL-UHFFFAOYSA-N, 2-CYCLOPROPYL-5-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE, AKOS015919285, CS-W006999, DS-2197, FD10110, SY028977, 6-cyclopropyl-3-pyridinylboronic acid pinacol ester, 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine, 2-Cyclopropyl-5-(4 pound not4 pound not5 pound not5-tetramethyl-1 pound not3 pound not2-dioxaborolan-2-yl)pyridine

Application

This compound is widely employed as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials via cross-coupling reactions. Its boronate ester group facilitates efficient Suzuki-Miyaura couplings with aryl halides, enabling the construction of complex biaryl systems. Researchers also use it to introduce cyclopropyl-pyridine motifs into drug candidates for enhanced metabolic stability. Additionally, it serves as a precursor in the development of boron-containing probes for chemical biology studies.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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