Description

2-Chloroethyl Methyl Ether (CAS 627-42-9) is a highly versatile organochlorine compound with the molecular formula C₃H₇ClO. Also known by its IUPAC name 1-chloro-2-methoxyethane, this clear, volatile liquid is widely used in organic synthesis and pharmaceutical research. Its reactive chloro and methoxy functional groups make it a valuable intermediate for alkylation, etherification, and nucleophilic substitution reactions. Suitable for laboratory and industrial applications, this reagent is rigorously tested for purity and stability. Store in a cool, dry place away from strong oxidizers and bases. Available in various packaging options to suit your research needs.

Properties

• CAS Number: 627-42-9
• Complexity: 16.4
• IUPAC Name: 1-chloro-2-methoxy-ethane
• InChI: InChI=1S/C3H7ClO/c1-5-3-2-4/h2-3H2,1H3
• InChI Key: XTIGGAHUZJWQMD-UHFFFAOYSA-N
• Exact Mass: 94.0185425
• Molecular Formula: C3H7ClO
• Molecular Weight: 94.54
• SMILES: COCCCl
• Topological: 9.2
• Monoisotopic Mass: 94.0185425
• Physical Description: Liquid;
• Boiling Point: 92-93 °C
• Solubility: SOL IN WATER; VERY SOL IN ETHER
• Density: 1.0345 @ 20 °C/4 °C
• Refractive Index: INDEX OF REFRACTION: 1.411 @ 20 °C/D
• Synonyms: 2-Chloroethyl methyl ether, 2-Methoxyethyl chloride, Ethane, 1-chloro-2-methoxy-, methoxyethyl chloride, Chloroethyl-methyl ether, methyl 2-chloroethyl ether, UNII-U890TJ10YM, Ethane, 1-chloro-2-methoxy, HSDB 2722, 2chloroethyl methyl ether, BETA-CHLOROETHYL METHYL ETHER, EINECS 210-999-7, 1-chloro-2-(methyloxy)ethane, AI3-61817, DTXSID6060840, 2-CHLORO-1-METHOXYETHANE, .BETA.-CHLOROETHYL METHYL ETHER, ETHYLENECHLOROHYDRIN METHYL ETHER, 1Chloro2methoxyethane, 2Methoxyethyl chloride, Ethane, 1chloro2methoxy, Ether, 2chloroethyl methyl, DTXCID3043499, 210-999-7, un3271, xtiggahuzjwqmd-uhfffaoysa-n, 627-42-9, 1-Chloro-2-methoxyethane, 1-chloro-2-methoxy-ethane, Ether, 2-chloroethyl methyl, 2-Methoxyethylchloride, U890TJ10YM, Chloro-2-methoxyethane, 2-Chloroethylmethylether, MFCD00000972, chloroethylmethylether, chloroethylmethyl ether, 2-methyloxychloroethane, chloroethyl methyl ether, 2-chloroethyl methylether, 2-chloroethyl-methylether, 2-chloroethylmethyl ether, 2-chloroethyl methy ether, 2-chloroethyl-methyl ether, 2-chloroethyl-methyl-ether, 1-(2-chloroethoxy)methane, 1-Chloro-2-methoxyethane #, SCHEMBL152874, SCHEMBL399961, SCHEMBL4416178, SCHEMBL6110733, SCHEMBL10848751, 2-Chloroethyl methyl ether, 98%, STL146567, AKOS000121076, 1-CHLORO-2-METHOXYETHANE [HSDB], DB-054268, NS00035156, EN300-23908, E77037, 2-Chloroethyl methyl ether; 2-Methoxyethyl chloride, Q27290851, F0001-1686

Application

2-Chloroethyl Methyl Ether is commonly employed as an alkylating agent in organic synthesis, particularly in the preparation of ethers and other functionalized compounds. It serves as a key intermediate in pharmaceutical manufacturing, aiding in the synthesis of active pharmaceutical ingredients (APIs). Researchers also utilize it in polymer chemistry for modifying polymer chains and in agrochemical production for developing specialized formulations.

Safety and Hazards

GHS Hazard Statements

• H225 (67.3%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H302 (75.2%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (36.3%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H331 (57.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]
• H332 (40.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P316, P317, P321, P330, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 2 (67.3%)
• Acute Tox. 4 (75.2%)
• Acute Tox. 4 (36.3%)
• Acute Tox. 3 (57.5%)
• Acute Tox. 4 (40.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.