Description

2-Chloro-5-fluorobenzoic acid (CAS No. 2252-50-8) is a high-purity aromatic carboxylic acid derivative widely used in pharmaceutical, agrochemical, and materials science research. With the molecular formula C₇H₄ClFO₂, this compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of active pharmaceutical ingredients (APIs) and fine chemicals. Its unique halogenated structure enhances reactivity in cross-coupling reactions, nucleophilic substitutions, and carboxylation processes. Our product is rigorously tested for purity (typically ≥98% by HPLC) and supplied with comprehensive analytical data (NMR, MS, FTIR). Packaged under inert conditions to ensure stability, it is ideal for demanding applications in medicinal chemistry and specialty chemical development.

Properties

• CAS Number: 2252-50-8
• Complexity: 163
• IUPAC Name: 2-chloro-5-fluoro-benzoic acid
• InChI: InChI=1S/C7H4ClFO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H,10,11)
• InChI Key: MIZKCMSSYVUZKD-UHFFFAOYSA-N
• Exact Mass: 173.9883852
• Molecular Formula: C7H4ClFO2
• Molecular Weight: 174.55
• SMILES: C1=CC(=C(C=C1F)C(=O)O)Cl
• Topological: 37.3
• Monoisotopic Mass: 173.9883852
• Synonyms: 2-Chloro-5-fluorobenzoic acid, 2252-50-8, DTXSID40307282, DTXCID60258409, 630-275-8, MFCD00156967, 2-chloro-5-fluoro-benzoic acid, 2-Chloro-5-fluorobenzoicacid, 5-Fluoro-2-chlorobenzoic acid, 2-chloro-5-fluoro benzoic acid, NSC190631, SCHEMBL786240, MIZKCMSSYVUZKD-UHFFFAOYSA-N, SBB063435, STK802600, AKOS005259289, AB04161, AC-3929, BS-3947, CS-W002454, NSC 190631, NSC-190631, NCGC00330744-01, SY019215, DB-011388, C2088, EN300-117645, AB01325247-02, Z1201619425

2-Chloro-5-fluorobenzoic acid is primarily employed as a key building block in the synthesis of biologically active compounds, including herbicides and anti-inflammatory drugs. Its dual halogen functionality enables selective modifications for structure-activity relationship (SAR) studies. Researchers also utilize it in metal-catalyzed coupling reactions to construct complex heterocycles. Suitable for use in both academic and industrial R&D environments under standard laboratory conditions.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (88.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (88.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.