Description

2-Chloro-4-methylbenzothiazole (CAS No. 3622-32-0) is a high-purity heterocyclic organic compound with the molecular formula C₈H₆ClNS. This benzothiazole derivative features a chloro substituent at the 2-position and a methyl group at the 4-position, offering unique reactivity for synthetic applications. With a molecular weight of 183.66 g/mol, it is a versatile building block in pharmaceutical, agrochemical, and material science research. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a crystalline solid with excellent batch-to-batch consistency. Ideal for nucleophilic substitution reactions, metal-catalyzed couplings, and as a precursor for functionalized benzothiazoles. Packaged under inert gas in amber glass vials to ensure stability.

Properties

• CAS Number: 3622-32-0
• Complexity: 153
• IUPAC Name: 2-chloro-4-methyl-1,3-benzothiazole
• InChI: InChI=1S/C8H6ClNS/c1-5-3-2-4-6-7(5)10-8(9)11-6/h2-4H,1H3
• InChI Key: NYNLRPVNVRAELQ-UHFFFAOYSA-N
• Exact Mass: 182.9909481
• Molecular Formula: C8H6ClNS
• Molecular Weight: 183.66
• SMILES: CC1=C2C(=CC=C1)SC(=N2)Cl
• Topological: 41.1
• Monoisotopic Mass: 182.9909481
• Synonyms: 2-Chloro-4-methylbenzothiazole, 3622-32-0, 2-chloro-4-methyl-1,3-benzothiazole, DTXSID00365944, DTXCID30316984, 967-770-6, 2-Chloro-4-methyl-benzothiazole, MFCD03840701, 2-Chloro-4-methyl-benzothiozole, 2-chloro-4-methylbenzo[d]thiazole, Benzothiazole, 2-chloro-4-methyl-, SCHEMBL1747925, SCHEMBL14127131, NYNLRPVNVRAELQ-UHFFFAOYSA-N, DAA62232, AKOS005208323, AB16506, AC-12080, AS-60338, SY038934, DB-027950, CS-0032535, EN300-236442, F15042, F1910-0001, Benzothiazole, 2-chloro-4-methyl- (6CI,7CI,8CI,9CI);2-Chloro-4-methyl-1,3-benzothiazole;

Application

2-Chloro-4-methylbenzothiazole serves as a key intermediate in the synthesis of bioactive molecules, particularly in the development of antimicrobial and antiviral agents. Its reactive chlorine atom enables facile functionalization for creating diverse benzothiazole libraries in medicinal chemistry. The compound is also employed in material science for constructing fluorescent dyes and organic electronic materials. Researchers utilize it as a scaffold for developing kinase inhibitors and other small-molecule therapeutics.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.