Description
2-Chloro-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine (CAS No. 267242-99-9) is a high-purity heterocyclic compound with the molecular formula C9H10ClN. This specialized chemical features a cyclopenta[b]pyridine core structure substituted with chloro and methyl functional groups at the 2- and 4-positions, respectively. With a molecular weight of 167.63 g/mol, this compound is supplied as a research-grade material with ≥95% purity (HPLC) and is ideal for pharmaceutical intermediates, organic synthesis, and medicinal chemistry applications. The product is characterized by 1H NMR, 13C NMR, and mass spectrometry for quality assurance. Store in a cool, dry place under inert atmosphere to maintain stability.
Properties
- CAS Number: 267242-99-9
- Complexity: 148
- IUPAC Name: 2-chloro-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine
- InChI: InChI=1S/C9H10ClN/c1-6-5-9(10)11-8-4-2-3-7(6)8/h5H,2-4H2,1H3
- InChI Key: JOJFZYVLQKMUQD-UHFFFAOYSA-N
- Exact Mass: 167.0501770
- Molecular Formula: C9H10ClN
- Molecular Weight: 167.63
- SMILES: CC1=CC(=NC2=C1CCC2)Cl
- Topological: 12.9
- Monoisotopic Mass: 167.0501770
- Synonyms: 2-Chloro-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine, 267242-99-9, 2-chloro-4-methyl-5H,6H,7H-cyclopenta[b]pyridine, MFCD08056605, 2-Chloro-6,7-dihydro-4-methyl-5H-cyclopenta[b]pyridine, 5H-Cyclopenta[b]pyridine, 2-chloro-6,7-dihydro-4-methyl-, SCHEMBL4928360, DTXSID80594699, AKOS005071867, BE-0729, SY322720, CS-0450534, W18956
Application
This compound serves as a versatile building block in the synthesis of pharmacologically active molecules, particularly in the development of kinase inhibitors and CNS-targeting agents. Researchers utilize it as a key intermediate for constructing fused pyridine derivatives with potential biological activity. The chloro and methyl substitutions allow for further functionalization via cross-coupling reactions or nucleophilic substitutions.
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