Description

2-Chloro-4-iodopyridine (CAS No. 153034-86-7) is a high-purity halogenated pyridine derivative widely used in pharmaceutical research, agrochemical development, and material science. This compound, with the molecular formula C₅H₃ClIN, serves as a versatile building block for synthesizing complex heterocyclic structures due to its reactive chloro and iodo substituents. Our product is rigorously tested to ensure ≥97% purity, making it ideal for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions. Packaged under inert gas to enhance stability, it features exceptional batch-to-batch consistency with detailed CoA documentation. Suitable for medicinal chemistry, CROs, and advanced organic synthesis laboratories.

Properties

• CAS Number: 153034-86-7
• Complexity: 78.8
• IUPAC Name: 2-chloro-4-iodo-pyridine
• InChI: InChI=1S/C5H3ClIN/c6-5-3-4(7)1-2-8-5/h1-3H
• InChI Key: KJKIPRQNFDUULB-UHFFFAOYSA-N
• Exact Mass: 238.89987
• Molecular Formula: C5H3ClIN
• Molecular Weight: 239.44
• SMILES: C1=CN=C(C=C1I)Cl
• Topological: 12.9
• Monoisotopic Mass: 238.89987
• Synonyms: 2-Chloro-4-iodopyridine, 153034-86-7, DTXSID70363977, DTXCID80315023, 628-020-0, 2-Chloro-4-iodo-pyridine, MFCD01861983, 4-Iodo-2-chloropyridine, PYRIDINE, 2-CHLORO-4-IODO-, 2-Chloro-4-Iodo Pyridine, SCHEMBL45635, SCHEMBL27674168, SCHEMBL29001795, 2-Chloro-4-iodopyridine, 97%, BCP13110, CS-D0941, BBL101557, SBB054361, STL555353, AKOS004910684, AC-4667, FC10407, PB17253, PS-7598, HY-32754, SY005539, DB-027604, C2089, ST51043276, EN300-95736

2-Chloro-4-iodopyridine is extensively employed as a key intermediate in palladium-catalyzed cross-coupling reactions to construct biaryl systems for drug discovery. It enables precise functionalization of pyridine cores in agrochemical active ingredients. Researchers utilize its halogen diversity for sequential derivatization in material science applications. The compound also serves as a precursor for fluorescent dyes and ligands in catalytic systems.

Safety and Hazards

GHS Hazard Statements

• H302 (92%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (82%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H318 (80%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (20%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (10%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (18%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (92%)
• Skin Irrit. 2 (20%)
• Skin Sens. 1 (82%)
• Eye Dam. 1 (80%)
• Eye Irrit. 2 (20%)
• Acute Tox. 4 (10%)
• STOT SE 3 (18%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.