Description

2-Chloro-4-fluorobenzyl alcohol (CAS No. 208186-84-9) is a high-purity fluorinated benzyl alcohol derivative with the molecular formula C₇H₆ClFO. This compound, also known by its IUPAC name (2-chloro-4-fluorophenyl)methanol, is a versatile building block in organic synthesis and pharmaceutical research. Its unique structure, featuring both chloro and fluoro substituents on the aromatic ring, makes it a valuable intermediate for the development of bioactive molecules, agrochemicals, and specialty materials.

Our product is rigorously tested to ensure >98% purity (HPLC/GC) and is supplied as a white to off-white crystalline solid with excellent batch-to-batch consistency. The compound is packaged under inert atmosphere to ensure stability and long shelf life. Technical data including ¹H/¹³C NMR spectra, mass spectrometry data, and HPLC chromatograms are available upon request.

Key applications include use as:

• Precursor for pharmaceutical intermediates
• Building block in medicinal chemistry
• Starting material for liquid crystal synthesis
• Intermediate for agrochemical development

Available in research quantities (100mg to 10g) and bulk scale (100g to kg quantities). Custom synthesis and contract manufacturing options available.

Properties

• CAS Number: 208186-84-9
• Complexity: 110
• IUPAC Name: (2-chloro-4-fluoro-phenyl)methanol
• InChI: InChI=1S/C7H6ClFO/c8-7-3-6(9)2-1-5(7)4-10/h1-3,10H,4H2
• InChI Key: ZUHMDLLAHZUDRE-UHFFFAOYSA-N
• Exact Mass: 160.0091207
• Molecular Formula: C7H6ClFO
• Molecular Weight: 160.57
• SMILES: C1=CC(=C(C=C1F)Cl)CO
• Topological: 20.2
• Monoisotopic Mass: 160.0091207
• Synonyms: 2-Chloro-4-fluorobenzyl alcohol, 208186-84-9, DTXSID70407224, DTXCID80358076, 670-709-3, (2-chloro-4-fluorophenyl)methanol, Benzenemethanol, 2-chloro-4-fluoro-, 2-Chloro-4-fluorobenzylalcohol, MFCD00236024, (2-chloro-4-fluorophenyl)methan-1-ol, SCHEMBL697564, SCHEMBL2089246, ZUHMDLLAHZUDRE-UHFFFAOYSA-N, Benzenemethanol,2-chloro-4-fluoro-, SBB006607, AKOS009159303, CS-W017935, SY003745, TS-02135, DB-018537, C2527, ST50405173, EN300-1232068

Application

2-Chloro-4-fluorobenzyl alcohol serves as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting CNS disorders and antimicrobial agents. The compound’s halogenated aromatic structure makes it valuable for developing PET radiotracers in medical imaging applications. Researchers also utilize this alcohol in materials science for creating specialized polymers with unique electronic properties.

Safety and Hazards

GHS Hazard Statements

• H302 (14.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (85.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (14.3%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (85.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.