Description

2-Bromothiophene (CAS No. 1003-09-4) is a high-purity brominated heterocyclic compound with the molecular formula C₄H₃BrS. This organobromine derivative of thiophene is widely utilized in organic synthesis, pharmaceutical research, and material science due to its reactive bromine substituent at the 2-position. Our product is rigorously tested to ensure >98% purity (GC), with trace metals and moisture levels minimized for sensitive applications. Supplied in amber glass bottles under inert gas to prevent degradation, it is ideal for cross-coupling reactions (e.g., Suzuki, Stille) and as a building block for conductive polymers, liquid crystals, and agrochemicals. Available in quantities from 1g to 1kg with customizable packaging.

• IUPAC Name: 2-bromothiophene
• Synonyms: 2-Thienyl bromide, Thiophene, 2-bromo-
• Molecular Weight: 163.03 g/mol
• Boiling Point: 150-152°C
• Density: 1.684 g/cm³ at 25°C
• Storage: 2-8°C under nitrogen

Properties

• CAS Number: 1003-09-4
• Complexity: 46.8
• IUPAC Name: 2-bromothiophene
• InChI: InChI=1S/C4H3BrS/c5-4-2-1-3-6-4/h1-3H
• InChI Key: TUCRZHGAIRVWTI-UHFFFAOYSA-N
• Exact Mass: 161.91388
• Molecular Formula: C4H3BrS
• Molecular Weight: 163.04
• SMILES: C1=CSC(=C1)Br
• Topological: 28.2
• Monoisotopic Mass: 161.91388
• Physical Description: Clear slightly brown liquid with a stench;
• Synonyms: 2-BROMOTHIOPHENE, 1003-09-4, Thiophene, 2-bromo-, 2-Thienyl bromide, GFF929NUW7, NSC 4456, NSC-4456, EINECS 213-699-4, DTXSID4061389, 2Thienyl bromide, Thiophene, 2bromo, DTXCID7032509, 213-699-4, inchi=1/c4h3brs/c5-4-2-1-3-6-4/h1-3, Thiophene, bromo-, Bromothiophene, 2-bromo-thiophene, 2-bromo thiophene, MFCD00005417, 60326-18-3, Thienyl bromide, 5-bromothiophene, NSC4456, 5-bromo-thiophene, 2-bromanylthiophene, 2-Bromothiophene, 98%, UNII-GFF929NUW7, SCHEMBL4057, SCHEMBL22395, BIDD:GT0231, SCHEMBL195893, SCHEMBL195925, SCHEMBL4767521, BCP21550, AC-194, SBB003931, AKOS000121588, CS-W020109, DS-1962, FB02219, PS-5772, DB-020745, B0941, NS00022968, ST50406225, EN300-20745, D77872, A800095, Q17487944, F0001-0036

Application

2-Bromothiophene serves as a key intermediate in the synthesis of thiophene-based pharmaceuticals, including antipsychotic and antiviral agents. It is extensively used in palladium-catalyzed cross-coupling reactions to create conjugated polymers for organic electronics (OLEDs, OFETs). In material science, it acts as a precursor for sulfur-containing liquid crystals and corrosion inhibitors. Researchers also employ it to modify surface properties of nanomaterials and as a ligand in catalytic systems.

Safety and Hazards

GHS Hazard Statements

• H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
• H300 (74.4%): Fatal if swallowed [Danger Acute toxicity, oral]
• H301 (25.6%): Toxic if swallowed [Danger Acute toxicity, oral]
• H310 (26.9%): Fatal in contact with skin [Danger Acute toxicity, dermal]
• H315 (29.5%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (70.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (29.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H330 (24.4%): Fatal if inhaled [Danger Acute toxicity, inhalation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P271, P280, P284, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (100%)
• Acute Tox. 2 (74.4%)
• Acute Tox. 3 (25.6%)
• Acute Tox. 2 (26.9%)
• Skin Irrit. 2 (29.5%)
• Eye Dam. 1 (70.5%)
• Eye Irrit. 2 (29.5%)
• Acute Tox. 2 (24.4%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.