Description

2-Bromoaniline (CAS No. 615-36-1) is a high-purity aromatic amine compound with the molecular formula C₆H₆BrN, widely utilized in organic synthesis and pharmaceutical research. This off-white to light brown crystalline solid exhibits a molecular weight of 172.02 g/mol and is characterized by its bromine substitution at the ortho position of the aniline ring, making it a valuable intermediate for coupling reactions and heterocyclic compound formation. With a melting point range of 59-62°C and boiling point of 229-230°C, 2-Bromoaniline is soluble in organic solvents like ethanol and ether while being sparingly soluble in water. Our product is rigorously tested via GC/HPLC to ensure ≥98% purity, meeting the stringent requirements of research laboratories and industrial applications. Proper storage at 2-8°C in tightly sealed amber vials ensures stability and prevents degradation.

Properties

• CAS Number: 615-36-1
• Complexity: 74.9
• IUPAC Name: 2-bromoaniline
• InChI: InChI=1S/C6H6BrN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2
• InChI Key: AOPBDRUWRLBSDB-UHFFFAOYSA-N
• Exact Mass: 170.96836
• Molecular Formula: C6H6BrN
• Molecular Weight: 172.02
• SMILES: C1=CC=C(C(=C1)N)Br
• Topological: 26
• Monoisotopic Mass: 170.96836
• Physical Description: Brown solid; mp = 27-32 deg C;
• Vapor Pressure: 0.04 [mmHg]
• Synonyms: 2-BROMOANILINE, Benzenamine, 2-bromo-, VTP98DS78E, NSC 7086, NSC-7086, EINECS 210-421-3, 2-AMINO-1-BROMOBENZENE, DTXSID5060645, oBromoaniline, Aniline, obromo, oAminobromobenzene, Benzenamine, 2bromo, Aniline, obromo (8CI), DTXCID0043054, 210-421-3, aopbdruwrlbsdb-uhfffaoysa-n, inchi=1/c6h6brn/c7-5-3-1-2-4-6(5)8/h1-4h,8h, un2811, 615-36-1, o-Bromoaniline, Aniline, o-bromo-, o-Aminobromobenzene, 2-bromobenzenamine, 2-bromo-aniline, 2-bromophenylamine, MFCD00007632, aniline, 2-bromo-, 2-bromioaniline, o-bromo-aniline, 2-bromaniline, 2-bromo aniline, ortho-bromoaniline, NSC7086, 2-bromo-phenylamine, 2-aminophenyl bromide, 2-Bromoaniline, 98%, UNII-VTP98DS78E, SCHEMBL70747, SCHEMBL232269, SCHEMBL232489, SCHEMBL652077, SCHEMBL1179675, SCHEMBL1179676, BCP27508, AC-153, SBB058717, STL264119, AKOS000119090, PS-5989, DB-024165, B0541, NS00010858, ST45255296, EN300-19059, A15699, F0001-1624, Z104472512

Application

2-Bromoaniline serves as a key building block in the synthesis of pharmaceuticals, agrochemicals, and dyes through Buchwald-Hartwig amination and Suzuki coupling reactions. Researchers employ this compound as a precursor for indole and quinoline derivatives in medicinal chemistry studies. The bromine substituent enables efficient functionalization via palladium-catalyzed cross-coupling, making it valuable for creating complex molecular architectures in drug discovery programs.

Safety and Hazards

GHS Hazard Statements

• H302 (96.2%): Harmful if swallowed [Warning Acute toxicity, oral]
• H311 (94.3%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H373 (96.2%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
• H411 (11.3%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P260, P262, P264, P270, P273, P280, P301+P317, P302+P352, P316, P319, P321, P330, P361+P364, P391, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (96.2%)
• Acute Tox. 3 (94.3%)
• STOT RE 2 (96.2%)
• Aquatic Chronic 2 (11.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.