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Atomfair 2-Bromo-6-(trifluoromethyl)aniline C7H5BrF3N CAS 58458-13-2

2-Bromo-6-(trifluoromethyl)aniline (CAS: 58458-13-2) is a high-purity aromatic amine derivative with the molecular formula C7H5BrF3N, widely utilized in pharmaceutical and agrochemical research. This compound features a bromo and trifluoromethyl functional group on the aniline ring, enhancing its reactivity and suitability for cross-coupling reactions, nucleophilic substitutions, and as a versatile intermediate in organic synthesis. With a molecular weight of 240.02 g/mol, it is supplied as a crystalline solid with >98% purity (HPLC), ensuring optimal performance in sensitive applications. Ideal for researchers developing novel fluorinated compounds, it is packaged under inert gas to maintain stability and stored at 2-8°C to prolong shelf life.…

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Description

2-Bromo-6-(trifluoromethyl)aniline (CAS: 58458-13-2) is a high-purity aromatic amine derivative with the molecular formula C7H5BrF3N, widely utilized in pharmaceutical and agrochemical research. This compound features a bromo and trifluoromethyl functional group on the aniline ring, enhancing its reactivity and suitability for cross-coupling reactions, nucleophilic substitutions, and as a versatile intermediate in organic synthesis. With a molecular weight of 240.02 g/mol, it is supplied as a crystalline solid with >98% purity (HPLC), ensuring optimal performance in sensitive applications. Ideal for researchers developing novel fluorinated compounds, it is packaged under inert gas to maintain stability and stored at 2-8°C to prolong shelf life. Available in quantities from 1g to 1kg, with customizable bulk options.

Properties

  • CAS Number: 58458-13-2
  • Complexity: 159
  • IUPAC Name: 2-bromo-6-(trifluoromethyl)aniline
  • InChI: InChI=1S/C7H5BrF3N/c8-5-3-1-2-4(6(5)12)7(9,10)11/h1-3H,12H2
  • InChI Key: BQSYRDIUPNIUGC-UHFFFAOYSA-N
  • Exact Mass: 238.95575
  • Molecular Formula: C7H5BrF3N
  • Molecular Weight: 240.02
  • SMILES: C1=CC(=C(C(=C1)Br)N)C(F)(F)F
  • Topological: 26
  • Monoisotopic Mass: 238.95575
  • Synonyms: 2-Bromo-6-(trifluoromethyl)aniline, 58458-13-2, EINECS 261-262-1, DTXSID00207158, DTXCID00129649, 261-262-1, 2-Amino-3-bromobenzotrifluoride, MFCD08741383, 2-bromo-6-trifluoromethylaniline, SCHEMBL459134, SBB099192, AKOS016005882, 6-bromo-2-(trifluoromethyl)phenylamine, PS-7592, SY308174, DB-364860, CS-0157248, NS00053168, EN300-123546

2-Bromo-6-(trifluoromethyl)aniline serves as a key building block in the synthesis of fluorinated pharmaceuticals, including potential kinase inhibitors and antimicrobial agents. Its electron-withdrawing trifluoromethyl group enhances metabolic stability in drug candidates, while the bromo substituent facilitates Suzuki-Miyaura and Buchwald-Hartwig couplings. Commonly employed in material science for creating liquid crystals and OLED precursors due to its rigid aromatic core. Compatible with Grignard reactions and palladium-catalyzed transformations.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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