Description

2-Bromo-6-(pyridin-2-yl)pyridine (CAS: 10495-73-5) is a high-purity heterocyclic organic compound with the molecular formula C₁₀H₇BrN₂. This brominated bipyridine derivative is a versatile building block in organic synthesis, particularly in the development of ligands for transition metal catalysis and pharmaceutical intermediates. Its rigid aromatic structure and reactive bromine moiety make it ideal for cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Available in >98% purity (HPLC), this compound is supplied as a white to off-white crystalline powder, rigorously tested for consistency and stability. Suitable for research in coordination chemistry, medicinal chemistry, and materials science. Store under inert conditions at 2-8°C to maintain optimal stability.

Properties

• CAS Number: 10495-73-5
• Complexity: 163
• IUPAC Name: 2-bromo-6-(2-pyridyl)pyridine
• InChI: InChI=1S/C10H7BrN2/c11-10-6-3-5-9(13-10)8-4-1-2-7-12-8/h1-7H
• InChI Key: NCRIDSGPLISUEU-UHFFFAOYSA-N
• Exact Mass: 233.97926
• Molecular Formula: C10H7BrN2
• Molecular Weight: 235.08
• SMILES: C1=CC=NC(=C1)C2=NC(=CC=C2)Br
• Topological: 25.8
• Monoisotopic Mass: 233.97926
• Synonyms: 2-bromo-6-(pyridin-2-yl)pyridine, 626-471-8, 6-BROMO-2,2′-BIPYRIDINE, 10495-73-5, 6-bromo-2,2′-bipyridyl, 2-bromo-6-pyridin-2-ylpyridine, MFCD01318953, 2-Bromo-6-(2-pyridyl)pyridine, 6-Bromo-2,2 inverted exclamation marka-bipyridine, 6-bromo-2-(2-pyridyl)pyridine, 2,2′-Bipyridine, 6-bromo-, 6-Bromo-2,2 inverted exclamation mark -bipyridine, 6-bromo-[2,2′]bipyridinyl, SCHEMBL353379, YSZC1721, DTXSID80472903, SMSSF-0625502, 6-Bromo-2,2′-bipyridine, 97%, SBB059648, AKOS005266604, AMS_CNC_ID-249459244, CS-W004576, DS-5999, SY055842, DB-027142, B4114, ST51044568, C71203, EN300-179985, AC-907/34107021

Application

2-Bromo-6-(pyridin-2-yl)pyridine serves as a key precursor in synthesizing N^N bidentate ligands for transition metal complexes used in homogeneous catalysis. It is employed in the preparation of luminescent materials and OLED intermediates due to its conjugated bipyridine scaffold. Researchers also utilize this compound in medicinal chemistry for the development of kinase inhibitors and other bioactive molecules targeting heterocyclic pharmacophores.

Safety and Hazards

GHS Hazard Statements

• H301 (95.3%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (95.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H335 (97.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (95.3%)
• Skin Irrit. 2 (97.7%)
• Eye Dam. 1 (95.3%)
• STOT SE 3 (97.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.