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Atomfair 2-Bromo-6-methylpyridin-3-amine C6H7BrN2 CAS 126325-53-9

2-Bromo-6-methylpyridin-3-amine (CAS: 126325-53-9) is a high-purity heterocyclic organic compound with the molecular formula C6H7BrN2. This versatile brominated pyridine derivative features an amine functional group at the 3-position and a methyl group at the 6-position, making it a valuable building block for pharmaceutical synthesis, agrochemical development, and material science applications. The compound is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring optimal performance in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions. Proper storage at 2-8°C under inert atmosphere is recommended to maintain stability. All batches undergo rigorous QC analysis including1H/13C NMR, LC-MS, and elemental analysis. Available in research…

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Description

2-Bromo-6-methylpyridin-3-amine (CAS: 126325-53-9) is a high-purity heterocyclic organic compound with the molecular formula C6H7BrN2. This versatile brominated pyridine derivative features an amine functional group at the 3-position and a methyl group at the 6-position, making it a valuable building block for pharmaceutical synthesis, agrochemical development, and material science applications. The compound is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring optimal performance in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions. Proper storage at 2-8°C under inert atmosphere is recommended to maintain stability. All batches undergo rigorous QC analysis including 1H/13C NMR, LC-MS, and elemental analysis. Available in research (100mg-1g), development (5-25g), and bulk (50g+) quantities with optional custom packaging.

Properties

  • CAS Number: 126325-53-9
  • Complexity: 97.1
  • IUPAC Name: 2-bromo-6-methyl-pyridin-3-amine
  • InChI: InChI=1S/C6H7BrN2/c1-4-2-3-5(8)6(7)9-4/h2-3H,8H2,1H3
  • InChI Key: KLVZEEUNGGOROA-UHFFFAOYSA-N
  • Exact Mass: 185.97926
  • Molecular Formula: C6H7BrN2
  • Molecular Weight: 187.04
  • SMILES: CC1=NC(=C(C=C1)N)Br
  • Topological: 38.9
  • Monoisotopic Mass: 185.97926
  • Synonyms: 126325-53-9, 2-BROMO-6-METHYLPYRIDIN-3-AMINE, DTXSID80560036, DTXCID80510814, 640-909-5, 3-Amino-2-bromo-6-picoline, 3-Amino-2-bromo-6-methylpyridine, 3-Pyridinamine, 2-bromo-6-methyl-, 2-BROMO-3-AMINE-6-METHYLPYRIDINE, MFCD03095078, 2-BROMO-6-METHYL-PYRIDIN-3-YLAMINE, SCHEMBL103351, 2-bromo-6-methyl-3-pyridylamine, KLVZEEUNGGOROA-UHFFFAOYSA-N, SBB051804, AKOS006346714, AB13459, AC-5428, PS-4397, (2-bromo-6-methyl-pyridin-3-yl)amine, 3-Amino-2-bromo-6-picoline, AldrichCPR, AC-27207, BL003774, SY012283, DB-003077, DB-008271, A2649, CS-0007528, EN300-102380

This brominated aminopyridine serves as a key intermediate in the synthesis of kinase inhibitors and receptor modulators, particularly in oncology research. The compound’s reactive bromine and amine groups enable efficient derivatization for structure-activity relationship studies. In material science, it functions as a precursor for conductive polymers and coordination complexes. The methyl group enhances lipophilicity for improved drug bioavailability in medicinal chemistry applications.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (66.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (66.7%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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