Atomfair

Awaiting product image

Atomfair 2-Bromo-6-fluorotoluene C7H6BrF

Description 2-Bromo-6-fluorotoluene (CAS No. 1422-54-4) is a high-purity halogenated aromatic compound with the molecular formula C7H6BrF and IUPAC name 1-bromo-3-fluoro-2-methylbenzene . This specialized chemical is rigorously synthesized and purified to meet the exacting standards of pharmaceutical, agrochemical, and materials science research. Its unique structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a versatile intermediate for cross-coupling reactions (e.g., Suzuki, Stille) and electrophilic aromatic substitutions. Available in quantities from milligrams to kilograms, our product undergoes thorough QC analysis (GC/HPLC, NMR) to ensure ??98% purity, with batch-specific certificates of analysis provided. Proper storage in amber glass under…

Category:
Brands:

Description

Description

2-Bromo-6-fluorotoluene (CAS No. 1422-54-4) is a high-purity halogenated aromatic compound with the molecular formula C7H6BrF and IUPAC name 1-bromo-3-fluoro-2-methylbenzene. This specialized chemical is rigorously synthesized and purified to meet the exacting standards of pharmaceutical, agrochemical, and materials science research. Its unique structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a versatile intermediate for cross-coupling reactions (e.g., Suzuki, Stille) and electrophilic aromatic substitutions. Available in quantities from milligrams to kilograms, our product undergoes thorough QC analysis (GC/HPLC, NMR) to ensure ??98% purity, with batch-specific certificates of analysis provided. Proper storage in amber glass under inert atmosphere is recommended to maintain stability.

  • CAS No: 1422-54-4
  • Molecular Formula: C7H6BrF
  • Molecular Weight: 189.02
  • Exact Mass: 187.96369
  • Monoisotopic Mass: 187.96369
  • IUPAC Name: 1-bromo-3-fluoro-2-methylbenzene
  • SMILES: CC1=C(C=CC=C1Br)F
  • Synonyms: 2-Bromo-6-fluorotoluene, 1422-54-4, 1-Bromo-3-fluoro-2-methylbenzene, DTXSID80371285, DTXCID40322319

Application

2-Bromo-6-fluorotoluene serves as a key building block in medicinal chemistry for the synthesis of fluorinated drug candidates, particularly kinase inhibitors and CNS-active compounds. Its orthogonal halogen/fluorine pattern enables sequential functionalization in Pd-catalyzed cross-couplings for scaffold diversification. The compound is also employed in liquid crystal and OLED material development, where the fluorine moiety modulates electronic properties. Researchers utilize it to introduce both bromine and fluorine handles for further derivatization in small molecule libraries.

If you are interested or have any questions, please contact us at support@atomfair.com