Description

2-Bromo-6-fluorobenzotrifluoride (CAS No. 261951-85-3) is a high-purity fluorinated aromatic compound with the molecular formula C₇H₃BrF₄. This specialized chemical, also known by its IUPAC name 1-bromo-3-fluoro-2-(trifluoromethyl)benzene, is a valuable building block in synthetic organic chemistry and pharmaceutical research. The compound features a benzene ring substituted with bromine, fluorine, and a trifluoromethyl group, offering unique electronic and steric properties for advanced chemical transformations.

Our product is rigorously tested to ensure exceptional quality, with typical purity levels exceeding 97% (GC analysis). It is supplied as a clear, colorless to pale yellow liquid with excellent batch-to-batch consistency. Proper handling requires storage under inert atmosphere at 2-8°C to maintain stability.

This reagent is particularly useful for:

• Transition metal-catalyzed cross-coupling reactions
• Nucleophilic aromatic substitution processes
• Preparation of fluorinated liquid crystals
• Synthesis of bioactive molecules in medicinal chemistry

Available in convenient packaging options from 1g to 1kg, with custom quantities available upon request. Technical data sheet and safety documentation provided with every order.

Properties

• CAS Number: 261951-85-3
• Complexity: 156
• IUPAC Name: 1-bromo-3-fluoro-2-(trifluoromethyl)benzene
• InChI: InChI=1S/C7H3BrF4/c8-4-2-1-3-5(9)6(4)7(10,11)12/h1-3H
• InChI Key: LOXSSZUHCPBDMD-UHFFFAOYSA-N
• Exact Mass: 241.93543
• Molecular Formula: C7H3BrF4
• Molecular Weight: 243.00
• SMILES: C1=CC(=C(C(=C1)Br)C(F)(F)F)F
• Monoisotopic Mass: 241.93543
• Synonyms: 2-Bromo-6-fluorobenzotrifluoride, 261951-85-3, 1-bromo-3-fluoro-2-(trifluoromethyl)benzene, DTXSID60378393, DTXCID00329420, 670-718-2, Benzene, 1-bromo-3-fluoro-2-(trifluoromethyl)-, 3-Fluoro-2-(trifluoromethyl)bromobenzene, MFCD01631569, 2-BROMO-ALPHA,ALPHA,ALPHA,6-TETRAFLUOROTOLUENE, SCHEMBL1091688, SCHEMBL1410432, SCHEMBL2289078, SCHEMBL28382957, 2-bromo-6-fluorobenzo trifluoride, BBL101395, CL8819, SBB099653, STL555191, AKOS005063725, AC-2332, CS-W014136, AS-19443, BP-11100, SY024103, 1-Bromo-3-fluoro-2-trifluoromethyl-benzene, DB-010808, B4833, EN300-131993, 6-bromo-2-fluorobenzotrifluoride;1-bromo-3-fluoro-2-(trifluoromethyl)benzene

Application

2-Bromo-6-fluorobenzotrifluoride serves as a versatile intermediate in pharmaceutical research, particularly in the development of fluorinated drug candidates where its unique substitution pattern enables precise modulation of biological activity. The compound is valuable in materials science for creating advanced fluorinated polymers with enhanced thermal and chemical resistance. Its electron-deficient aromatic ring makes it particularly useful in palladium-catalyzed cross-coupling reactions for constructing complex molecular architectures.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (75%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (75%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.