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Atomfair 2-Bromo-6-fluorobenzoic acid C7H4BrFO2

Description 2-Bromo-6-fluorobenzoic acid (CAS No. 2252-37-1) is a high-purity halogenated benzoic acid derivative with the molecular formula C7H4BrFO2. This fine chemical is a valuable building block in synthetic organic chemistry, particularly in pharmaceutical and agrochemical research. The compound features both bromine and fluorine substituents on the aromatic ring, offering unique reactivity for cross-coupling reactions, nucleophilic substitutions, and other transformations. Our product is rigorously tested to ensure >98% purity (HPLC) and is supplied as a white to off-white crystalline powder. Suitable for use in medicinal chemistry, material science, and as a precursor for advanced intermediates. Packaged under inert gas to ensure…

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Description

Description

2-Bromo-6-fluorobenzoic acid (CAS No. 2252-37-1) is a high-purity halogenated benzoic acid derivative with the molecular formula C7H4BrFO2. This fine chemical is a valuable building block in synthetic organic chemistry, particularly in pharmaceutical and agrochemical research. The compound features both bromine and fluorine substituents on the aromatic ring, offering unique reactivity for cross-coupling reactions, nucleophilic substitutions, and other transformations. Our product is rigorously tested to ensure >98% purity (HPLC) and is supplied as a white to off-white crystalline powder. Suitable for use in medicinal chemistry, material science, and as a precursor for advanced intermediates. Packaged under inert gas to ensure stability and shipped with comprehensive analytical data (NMR, MS, HPLC).

  • CAS No: 2252-37-1
  • Molecular Formula: C7H4BrFO2
  • Molecular Weight: 219.01
  • Exact Mass: 217.93787
  • Monoisotopic Mass: 217.93787
  • IUPAC Name: 2-bromo-6-fluorobenzoic acid
  • SMILES: C1=CC(=C(C(=C1)Br)C(=O)O)F
  • Synonyms: 2-BROMO-6-FLUOROBENZOIC ACID, DTXSID90307156, DTXCID20258283, 630-262-7, 2252-37-1

Application

2-Bromo-6-fluorobenzoic acid serves as a versatile intermediate in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions for drug discovery. The compound is particularly useful in the synthesis of fluorinated bioactive molecules due to its orthogonal reactivity. Researchers employ this building block in developing kinase inhibitors, PET radiotracer precursors, and liquid crystal materials. The fluorine moiety enhances metabolic stability in pharmaceutical candidates while the bromine enables further functionalization.

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