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Atomfair 2-Bromo-5-methylbenzotrifluoride C8H6BrF3

Description 2-Bromo-5-methylbenzotrifluoride (CAS No. 261952-20-9) is a high-purity halogenated aromatic compound with the molecular formula C8H6BrF3. This specialized chemical, also known by its IUPAC name 1-bromo-4-methyl-2-(trifluoromethyl)benzene , features a trifluoromethyl group and a bromine substituent on a methylated benzene ring, making it a valuable intermediate in synthetic organic chemistry. Its unique structure offers excellent reactivity for cross-coupling reactions, nucleophilic substitutions, and as a building block for pharmaceuticals, agrochemicals, and advanced materials. Supplied as a clear to pale-yellow liquid, it is rigorously tested for purity (typically ??97% by GC) and stored under inert conditions to ensure stability. Ideal for researchers in…

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Description

Description

2-Bromo-5-methylbenzotrifluoride (CAS No. 261952-20-9) is a high-purity halogenated aromatic compound with the molecular formula C8H6BrF3. This specialized chemical, also known by its IUPAC name 1-bromo-4-methyl-2-(trifluoromethyl)benzene, features a trifluoromethyl group and a bromine substituent on a methylated benzene ring, making it a valuable intermediate in synthetic organic chemistry. Its unique structure offers excellent reactivity for cross-coupling reactions, nucleophilic substitutions, and as a building block for pharmaceuticals, agrochemicals, and advanced materials. Supplied as a clear to pale-yellow liquid, it is rigorously tested for purity (typically ??97% by GC) and stored under inert conditions to ensure stability. Ideal for researchers in medicinal chemistry, material science, and catalysis.

  • CAS No: 261952-20-9
  • Molecular Formula: C8H6BrF3
  • Molecular Weight: 239.03
  • Exact Mass: 237.96050
  • Monoisotopic Mass: 237.96050
  • IUPAC Name: 1-bromo-4-methyl-2-(trifluoromethyl)benzene
  • SMILES: CC1=CC(=C(C=C1)Br)C(F)(F)F
  • Synonyms: 2-bromo-5-methylbenzotrifluoride, 261952-20-9, DTXSID10381397, DTXCID30332422, 1-bromo-4-methyl-2-(trifluoromethyl)benzene

Application

2-Bromo-5-methylbenzotrifluoride is widely used as a key intermediate in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to synthesize complex aromatic systems. Its electron-withdrawing trifluoromethyl group enhances reactivity in nucleophilic aromatic substitutions, making it valuable for pharmaceutical and agrochemical development. The compound is also employed in the synthesis of liquid crystals and specialty polymers due to its thermal stability and halogenated aromatic core.

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