Description

Description

2-Bromo-5-fluoroaniline (CAS No. 1003-99-2) is a high-purity halogenated aniline derivative with the molecular formula C₆H₅BrFN. This aromatic amine features both bromine and fluorine substituents on the benzene ring, making it a versatile intermediate for pharmaceutical, agrochemical, and materials science research. Its IUPAC name, 2-bromo-5-fluoroaniline, reflects its precise structural configuration, where the bromo and fluoro groups are ortho and meta to the amino group, respectively. This compound is supplied as a crystalline solid or solution, with >98% purity verified by GC/HPLC, and is packaged under inert gas to ensure stability. Ideal for Suzuki couplings, Buchwald-Hartwig aminations, and other cross-coupling reactions, it is a critical building block for synthesizing bioactive molecules and advanced materials. Store in a cool, dry place away from light and oxidizing agents.

Application

2-Bromo-5-fluoroaniline is widely used as a key intermediate in the synthesis of pharmaceuticals, particularly for constructing fluorinated and brominated heterocycles. It serves as a precursor in the development of agrochemicals, such as herbicides and fungicides, leveraging its halogenated aromatic structure. Researchers also employ it in material science to engineer organic semiconductors and liquid crystals due to its electron-withdrawing properties. Its reactivity in palladium-catalyzed cross-coupling reactions makes it valuable for creating complex molecular architectures.

If you are interested or have any questions, please contact us at support@atomfair.com