Description

2-Bromo-4-pyridinecarboxaldehyde (CAS No. 118289-17-1) is a high-purity heterocyclic aldehyde with the molecular formula C₆H₄BrNO. This compound, also known as 2-bromopyridine-4-carbaldehyde, is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its reactive aldehyde and bromo groups enable selective functionalization, making it ideal for cross-coupling reactions, nucleophilic substitutions, and as a precursor for ligands or catalysts. Supplied as a crystalline solid with ≥95% purity (HPLC), it is rigorously tested for consistency and stability. Store under inert conditions at 2-8°C to prevent degradation. Suitable for use in medicinal chemistry, material science, and as an intermediate in multi-step syntheses.

Properties

• CAS Number: 118289-17-1
• Complexity: 107
• IUPAC Name: 2-bromopyridine-4-carbaldehyde
• InChI: InChI=1S/C6H4BrNO/c7-6-3-5(4-9)1-2-8-6/h1-4H
• InChI Key: RTWLIQFKXMWEJY-UHFFFAOYSA-N
• Exact Mass: 184.94763
• Molecular Formula: C6H4BrNO
• Molecular Weight: 186.01
• SMILES: C1=CN=C(C=C1C=O)Br
• Topological: 30
• Monoisotopic Mass: 184.94763
• Synonyms: 118289-17-1, 2-Bromo-4-pyridinecarboxaldehyde, 624-388-1, 2-Bromopyridine-4-carboxaldehyde, 2-bromopyridine-4-carbaldehyde, 2-bromoisonicotinaldehyde, 2-Bromo-4-formylpyridine, 4-Pyridinecarboxaldehyde, 2-bromo-, MFCD04039311, 2-Bromo-4-pyridinecarbaldehyde, PD3R2TVE77, SCHEMBL567210, 2-Bromo-pyridin-4-carbaldehyde, 2-bromo-pyridine-4-carbaldehyde, SCHEMBL20448774, DTXSID10376642, BBL100855, CL8873, SBB052237, STL554649, AKOS005255204, AB17326, CS-W007762, 2-Bromo-4-pyridinecarboxaldehyde, 98%, AC-24348, DB-010982, B3715, ST50827802, EN300-106493, 2-Bromoisonicotinaldehyde; 2-Bromopyridine-4-carboxaldehyde

Application

2-Bromo-4-pyridinecarboxaldehyde is widely used as a key intermediate in the synthesis of pharmaceuticals, including kinase inhibitors and antiviral agents. Its bromo and aldehyde functionalities facilitate Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions. Researchers also employ it to construct pyridine-based ligands for metal-organic frameworks (MOFs) and catalysts. In agrochemical development, it serves as a precursor for herbicides and fungicides.

Safety and Hazards

GHS Hazard Statements

• H302 (89.1%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (89.1%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (97.8%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.