Description

Description

2-Bromo-4-fluoro-1-iodobenzene (CAS No. 202865-73-4) is a high-purity halogenated aromatic compound with the molecular formula C₆H₃BrFI. This versatile intermediate is widely used in organic synthesis, pharmaceutical research, and material science due to its reactive halogen substituents. The compound features bromine, fluorine, and iodine atoms at the 2-, 4-, and 1-positions of the benzene ring, respectively, enabling selective functionalization via cross-coupling reactions such as Suzuki, Stille, or Sonogashira couplings.

Our product is rigorously tested for purity (typically ??97% by GC or HPLC) and is supplied in sealed, light-resistant packaging to ensure stability. Ideal for researchers developing novel agrochemicals, pharmaceuticals, or liquid crystal materials, this compound offers excellent reactivity for constructing complex molecular architectures. Storage under inert atmosphere at 2-8??C is recommended for long-term stability.

Application

2-Bromo-4-fluoro-1-iodobenzene serves as a key building block in pharmaceutical synthesis, particularly for creating fluorinated drug candidates. The compound’s multiple halogen sites enable sequential functionalization in Pd-catalyzed cross-coupling reactions. Researchers utilize this intermediate in the development of liquid crystal materials for display technologies due to its polarizable iodine substituent. It also finds application in agrochemical research for constructing fluorinated pesticides with enhanced bioactivity.

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