Description

2-Bromo-4-chloro-6-(trifluoromethyl)aniline (CAS No. 912617-74-4) is a high-purity halogenated aniline derivative with the molecular formula C₇H₄BrClF₃N. This compound features a trifluoromethyl group and halogen substituents (bromo and chloro) on the aromatic ring, making it a versatile intermediate for advanced organic synthesis. It is supplied as a crystalline solid with guaranteed purity (>98%) by HPLC, ideal for pharmaceutical, agrochemical, and materials science research. The product is rigorously tested for consistency, stability, and absence of impurities, ensuring reliable performance in demanding applications. Store in a cool, dry place under inert conditions to maintain optimal stability.

Properties

• CAS Number: 912617-74-4
• Complexity: 187
• IUPAC Name: 2-bromo-4-chloro-6-(trifluoromethyl)aniline
• InChI: InChI=1S/C7H4BrClF3N/c8-5-2-3(9)1-4(6(5)13)7(10,11)12/h1-2H,13H2
• InChI Key: BSWOSDJUIAUNLF-UHFFFAOYSA-N
• Exact Mass: 272.91677
• Molecular Formula: C7H4BrClF3N
• Molecular Weight: 274.46
• SMILES: C1=C(C=C(C(=C1C(F)(F)F)N)Br)Cl
• Topological: 26
• Monoisotopic Mass: 272.91677
• Synonyms: 2-Bromo-4-chloro-6-(trifluoromethyl)aniline, 912617-74-4, 2-Amino-3-bromo-5-chlorobenzotrifluoride, 2-bromo-4-chloro-6-trifluoromethylaniline, MFCD08436083, SCHEMBL10215752, DTXSID80584853, BSWOSDJUIAUNLF-UHFFFAOYSA-N, AKOS015835101, BS-29683, SY104135, DB-364776, CS-0188471, E85361, EN300-396621, 2-Bromo-4-chloro-6-(trifluoromethyl)aniline, 97%

Application

2-Bromo-4-chloro-6-(trifluoromethyl)aniline is a key building block in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its reactive amino and halogen groups enable participation in cross-coupling reactions, such as Buchwald-Hartwig amination or Suzuki-Miyaura coupling. The trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable in drug discovery. Researchers also utilize it to develop specialty polymers and liquid crystals with unique electronic properties.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.