Description

Description

2-Bromo-3-methylpyridine (CAS No. 3430-17-9) is a high-purity heterocyclic organic compound with the molecular formula C₆H₆BrN. This versatile brominated pyridine derivative is an essential intermediate in pharmaceutical, agrochemical, and material science research. Its molecular weight of 172.02 g/mol and distinct reactivity make it ideal for cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings, as well as nucleophilic substitutions.

Available in >98% purity (GC), this compound is supplied as a clear to pale yellow liquid with a characteristic pyridine odor. It is packaged under inert gas to ensure stability and shipped with detailed analytical certificates (including ¹H NMR, ¹³C NMR, and GC-MS data). Store at 2-8??C in tightly sealed containers away from light and moisture.

Key applications include: building block for kinase inhibitors, ligand synthesis in catalysis, and functional material development. Compatible with anhydrous reactions and organometallic chemistry.

Application

2-Bromo-3-methylpyridine serves as a critical precursor in medicinal chemistry for developing tyrosine kinase inhibitors and other bioactive molecules. Its bromine moiety enables efficient palladium-catalyzed cross-coupling reactions to construct complex heterocyclic systems. Researchers also utilize this compound as a directing group in C-H activation chemistry and as a scaffold for N-heterocyclic carbene ligands in transition metal catalysis.

If you are interested or have any questions, please contact us at support@atomfair.com