Description

2-Aminopyrazine (CAS No. 5049-61-6) is a high-purity heterocyclic organic compound with the molecular formula C₄H₅N₃. This versatile chemical building block features an amino group attached to the pyrazine ring, making it a valuable intermediate in pharmaceutical synthesis, agrochemical development, and material science research. Our product is rigorously tested to ensure >98% purity by HPLC analysis, with full characterization including ¹H NMR, ¹³C NMR, and mass spectrometry data available. Supplied as a white to off-white crystalline powder with excellent solubility in polar organic solvents (DMSO, methanol, ethanol), it’s packaged under inert atmosphere in amber glass vials to ensure stability. Ideal for medicinal chemistry applications, this compound serves as a key precursor for nucleoside analogs, kinase inhibitors, and other bioactive molecules. Technical specifications include: molecular weight 95.11 g/mol, melting point 120-122°C, and density 1.25 g/cm³. SDS and COA documentation provided with each shipment.

Properties

• CAS Number: 5049-61-6
• Complexity: 54.9
• IUPAC Name: pyrazin-2-amine
• InChI: InChI=1S/C4H5N3/c5-4-3-6-1-2-7-4/h1-3H,(H2,5,7)
• InChI Key: XFTQRUTUGRCSGO-UHFFFAOYSA-N
• Exact Mass: 95.048347172
• Molecular Formula: C4H5N3
• Molecular Weight: 95.10
• SMILES: C1=CN=C(C=N1)N
• Topological: 51.8
• Monoisotopic Mass: 95.048347172
• Synonyms: 2-Aminopyrazine, pyrazin-2-amine, 5049-61-6, Aminopyrazine, Pyrazinamine, 2-Pyrazinamine, ES73FRK6MY, EINECS 225-748-7, NSC-13147, AI3-60202, DTXSID80198510, NSC 13147, DTXCID40121001, 225-748-7, inchi=1/c4h5n3/c5-4-3-6-1-2-7-4/h1-3h,(h2,5,7, pyrazin-2-ylamine, Pyrazine, 2-amino-, MFCD00006137, CHEMBL1834089, ENT 60202, AMINO PYRAZINE, iminopyrazine, pyrazineamine, amino-pyrazine, Pyrazinamine-, Pyrazine amine, 2-aminopyrazin, 2 -aminopyrazine, 2-amino pyrazine, 2-amino-pyrazine, pyrazine-2-amine, Pyrazine, amino-, Pyrazine, 1,2-dihydro-2-imino-, 2-Pyrazinamine #, pyrazine-2-ylamine, Pyrazin-2-yl-amine, Aminopyrazine, 98%, 3-AMINOPYRAZINE, UNII-ES73FRK6MY, SCHEMBL29032, 1,2-Dihydro-2-iminopyrazine, Pyrazine,2-dihydro-2-imino-, SCHEMBL152044, SCHEMBL295729, SCHEMBL432791, SCHEMBL558752, SCHEMBL747516, SCHEMBL2959998, CHEBI:194609, BCP13854, CS-D1606, NSC13147, BDBM50354830, CL4536, SBB004388, STL137799, AKOS000120229, PB30528, PS-9353, NCGC00188272-01, AC-23436, BP-21335, HY-34068, PD020349, SY001512, DB-022479, A0989, NS00032070, EN300-17193, AC-907/25014024, Z56899063, F2169-0758

2-Aminopyrazine serves as a crucial building block in pharmaceutical research, particularly in the development of antiviral and anticancer agents. Its reactive amino group enables facile derivatization for creating diverse heterocyclic scaffolds in medicinal chemistry. Researchers utilize this compound in synthesizing nucleoside analogs that mimic natural purine bases. In material science, it functions as a ligand for transition metal complexes used in catalytic systems. The compound also finds application in agrochemical research for developing novel crop protection agents.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (96%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.