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Atomfair 2-Amino-5-fluorophenol C6H6FNO

Description 2-Amino-5-fluorophenol (CAS No. 53981-24-1) is a high-purity fluorinated aromatic compound with the molecular formula C6H6FNO . This fine chemical is an essential intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its structure features an amino group (-NH2) and a hydroxyl group (-OH) ortho to each other on a fluorinated benzene ring, making it a versatile building block for heterocyclic compounds and active pharmaceutical ingredients (APIs). Our product is rigorously tested for purity (typically ??98% by HPLC or GC analysis) and is supplied as a crystalline solid with excellent batch-to-batch consistency. Proper storage conditions (2-8??C in a…

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Description

Description

2-Amino-5-fluorophenol (CAS No. 53981-24-1) is a high-purity fluorinated aromatic compound with the molecular formula C6H6FNO. This fine chemical is an essential intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its structure features an amino group (-NH2) and a hydroxyl group (-OH) ortho to each other on a fluorinated benzene ring, making it a versatile building block for heterocyclic compounds and active pharmaceutical ingredients (APIs).

Our product is rigorously tested for purity (typically ??98% by HPLC or GC analysis) and is supplied as a crystalline solid with excellent batch-to-batch consistency. Proper storage conditions (2-8??C in a tightly sealed container under inert atmosphere) ensure long-term stability. Suitable for research-scale applications and process development in medicinal chemistry, this compound is particularly valuable for synthesizing fluorinated analogs of biologically active molecules.

Key applications include use as a precursor in:

  • Fluorinated benzoxazole synthesis
  • Pharmaceutical intermediates
  • Agrochemical development
  • Materials science research

Safety Information: Handle with appropriate personal protective equipment (PPE) in a well-ventilated area. Refer to the SDS for complete handling and disposal guidelines.

  • CAS No: 53981-24-1
  • Molecular Formula: C6H6FNO
  • Molecular Weight: 127.12
  • Exact Mass: 127.043341977
  • Monoisotopic Mass: 127.043341977
  • IUPAC Name: 2-amino-5-fluorophenol
  • SMILES: C1=CC(=C(C=C1F)O)N
  • Synonyms: 2-Amino-5-fluorophenol, 640-241-4, 53981-24-1, 4-Fluoro-2-hydroxyaniline, Phenol, 2-amino-5-fluoro-

Application

2-Amino-5-fluorophenol serves as a key intermediate in the synthesis of fluorinated heterocyclic compounds, particularly benzoxazoles with potential pharmaceutical activity. The compound’s orthogonal functional groups enable diverse chemical transformations, making it valuable for structure-activity relationship studies in drug discovery. Researchers utilize this building block to develop fluorinated analogs of bioactive molecules, leveraging the fluorine atom’s ability to modulate pharmacokinetic properties. In materials science, it finds application in the preparation of fluorinated polymers and specialty chemicals.

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